Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03598166 · ClinicalTrials.gov registry record · NA
Assessing the Effect of a Blood-based Colorectal Cancer Screening Test on Screening Adherence and Colonoscopy Completion
A NA study of Colorectal Cancer, sponsored by Peter S. Liang, MD MPH.
- Completed
- Registry status
- NA
- Development phase
- 359
- Enrollment target
- 1
- Study location
NCT03598166: Completed NA study of Colorectal Cancer, sponsored by Peter S. Liang, MD MPH.
NCT03598166 is a NA study of Colorectal Cancer that has completed, run by Peter S. Liang, MD MPH. The registered enrollment target is 359 participants, below the 1,510-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03598166, a NA study of Colorectal Cancer, has completed, sponsored by Peter S. Liang, MD MPH.
- COMPLETED
- Registry status
- NA
- Development phase
- 359 participants
- Enrollment target
- 1
- Study location
Study Summary
Objectives: Colonoscopy and stool-based testing are the two predominant colorectal cancer (CRC) screening tests used in the US, and both reduce colorectal cancer mortality. However, only 62% of Americans are up to date with screening, partly because many individuals find these two tests inconvenient or unacceptable for a variety of reasons. There is an unmet need for a non-invasive test that does not require bowel preparation or handling stool, and the Septin9 DNA blood test may be an alternative for those individuals who would otherwise remain unscreened. Aims: Aim 1: To measure screening uptake with a blood test in screen-resistant patients who have declined both colonoscopy and fecal immunochemical testing (FIT) at the Manhattan VA Medical Center * Sub-Aim 1a: To assess the proportion of those with a positive blood-based screening test who undergo diagnostic colonoscopy * Sub-Aim 1b: To describe the endoscopic findings on diagnostic colonoscopy Aim 2: To survey screen-resistant patients to understand their beliefs and attitudes about colorectal cancer screening and testing options We hypothesize that a substantial proportion of patients who have refused colonoscopy and FIT will accept the blood test. We hypothesize this will be driven by the convenience of the blood test. Methods: This will be randomized controlled trial of individuals who have refused colonoscopy and FIT within past 6 months. Eligible patients will be randomized 1:1 to the intervention or control group. Both groups will be invited to participate in navigated colonoscopy or FIT by letter and telephone call. The intervention group will also be invited to participate in the blood test if they refuse colonoscopy and FIT. We will enroll 180 participants in each group (total n=360).
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Septin9
Study Locations (1)
New York
- VA New York Harbor Health Care System - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 359 participants |
| Start Date | 2018-10-11 |
| Est. Completion | 2020-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03598166
The ClinicalTrials.gov registry entry for NCT03598166 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 359 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,510-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (76% lower). The listed sponsor is Peter S. Liang, MD MPH, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention - of which Septin9 is the first listed.
NCT03598166 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT03598166 about?
NCT03598166 is a clinical study titled "Assessing the Effect of a Blood-based Colorectal Cancer Screening Test on Screening Adherence and Colonoscopy Completion". Objectives: Colonoscopy and stool-based testing are the two predominant colorectal cancer (CRC) screening tests used in the US, and both reduce colorectal cancer mortality. However, only 62% of Americans are up to date with screening, partly because many individuals find these two tests inconvenien...
What is the current status of trial NCT03598166?
This trial is currently completed. It is a NA study. The enrollment target is 359 participants. The study started on 2018-10-11. Estimated completion is 2020-12-31.
What conditions does trial NCT03598166 study?
This clinical trial studies the following conditions: Colorectal Cancer.
What interventions are being tested in trial NCT03598166?
The interventions under investigation include: Septin9 (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03598166?
This trial is sponsored by Peter S. Liang, MD MPH, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03598166 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colorectal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
A Cross-sectional Partnership to Improve Prevention and Health Equity Among African Americans
RECRUITING · NA
-
Precise Oncology Interventions in Nutrition and Training (OnPoint)
RECRUITING · NA
-
Resistance Exercise and Creatine in Colorectal Cancer
RECRUITING · NA
-
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
RECRUITING · NA
-
Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal Cancer
RECRUITING · NA
-
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer
RECRUITING · NA
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.