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NCT03592277 · ClinicalTrials.gov registry record · Phase 2
Vitamin C & Thiamine to Treat Sepsis and Septic Shock
A Phase 2 study, sponsored by Trinity Health Of New England.
- Completed
- Registry status
- Phase 2
- Development phase
- 120
- Enrollment target
NCT03592277: Completed Phase 2 study, sponsored by Trinity Health Of New England.
NCT03592277 is a Phase 2 study that has completed, run by Trinity Health Of New England. The registered enrollment target is 120 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03592277, a Phase 2 study, has completed, sponsored by Trinity Health Of New England.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 120 participants
- Enrollment target
Study Summary
Investigators propose to investigate the use of IV vitamins B1 and C in a randomized, double-blinded, prospective trial to determine if these medications decrease mortality rates in patients with severe sepsis or septic shock.
Primary Outcome
All-cause mortality from time of enrollment/treatment to 30 days post hospital discharge (up to 87 days)
Interventions
- DRUG Vitamin C
- DRUG Vitamin B1
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2018-09-14 |
| Est. Completion | 2021-02-22 |
| Phase | Phase 2 |
What the finished NCT03592277 record still lists
NCT03592277 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% lower).
The record links to 0 conditions, and to 2 interventions - of which Vitamin C is the first listed.
NCT03592277 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03592277 about?
NCT03592277 is a clinical study titled "Vitamin C & Thiamine to Treat Sepsis and Septic Shock". Investigators propose to investigate the use of IV vitamins B1 and C in a randomized, double-blinded, prospective trial to determine if these medications decrease mortality rates in patients with severe sepsis or septic shock.
What is the current status of trial NCT03592277?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 120 participants. The study started on 2018-09-14. Estimated completion is 2021-02-22.
What interventions are being tested in trial NCT03592277?
The interventions under investigation include: Vitamin C (DRUG), Vitamin B1 (DRUG).
Who is sponsoring clinical trial NCT03592277?
This trial is sponsored by Trinity Health Of New England, which has 20 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03592277's enrollment target sits among peer trials
120 569th of 2000 higher than 1,383 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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