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NCT03592238 · ClinicalTrials.gov registry record · NA
Sympathetic Nervous System Mediation of Acute Exercise Effects on Childhood Brain and Cognition
A NA study, sponsored by Northeastern University.
- Completed
- Registry status
- NA
- Development phase
- 297
- Enrollment target
NCT03592238 is a NA study that has completed, run by Northeastern University. The registered enrollment target is 297 participants.
The verdict
NCT03592238, a NA study, has completed, sponsored by Northeastern University.
- COMPLETED
- Registry status
- NA
- Development phase
- 297 participants
- Enrollment target
Study Summary
Today's children have become increasingly inactive and unfit, with \>50% of children not meeting the recommended 60 min of moderate-to-vigorous physical activity. Previous research has suggested that acute aerobic exercise of moderate intensity was associated with improved cognition manifested by improved performance and increased P3 amplitude, a neuroelectric indicator that reflects the amount of attentional allocation, in tasks requiring cognitive control. While minimal evidence exists to support potential mechanisms underlying the transient effects of exercise on brain and cognition, research suggests that phasic changes in the locus coeruleus-norepinephrine (LC-NE) (as measured by salivary alpha amylase (sAA)) system are a potential mechanism for explaining the acute effect of exercise on brain and cognition. Accordingly, the aim of this study is to examine the mechanisms linking acute aerobic exercise to improved cognitive control as well as the underlying neuroelectrical activities in children, using electroencephalography (EEG) and event-related potentials (ERPs). We hope to gain a better understanding of the role of acute exercise and cognitive and brain health. The results from this study will help identify mechanisms linking acute exercise to enhanced cognitive performance in children. Our hypothesis is that exercise-induced phasic increases in sympathetic nervous system activity will mediate the effect of a single bout of exercise on brain function, cognition, and standardized achievement test performance.
Interventions
- OTHER Aerobic Exercise Intervention
- OTHER Trier Social Stress Test for Children
- OTHER Seated Rest
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 297 participants |
| Start Date | 2019-02-10 |
| Est. Completion | 2024-06-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03592238
The ClinicalTrials.gov registry entry for NCT03592238 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 297 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northeastern University, which has 39 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Aerobic Exercise Intervention is the first listed.
NCT03592238 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03592238 about?
NCT03592238 is a clinical study titled "Sympathetic Nervous System Mediation of Acute Exercise Effects on Childhood Brain and Cognition". Today's children have become increasingly inactive and unfit, with \>50% of children not meeting the recommended 60 min of moderate-to-vigorous physical activity. Previous research has suggested that acute aerobic exercise of moderate intensity was associated with improved cognition manifested by im...
What is the current status of trial NCT03592238?
This trial is currently completed. It is a NA study. The enrollment target is 297 participants. The study started on 2019-02-10. Estimated completion is 2024-06-30.
What interventions are being tested in trial NCT03592238?
The interventions under investigation include: Aerobic Exercise Intervention (OTHER), Trier Social Stress Test for Children (OTHER), Seated Rest (OTHER).
Who is sponsoring clinical trial NCT03592238?
This trial is sponsored by Northeastern University, which has 39 total clinical trials registered on ClinicalTrials.gov.
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