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NCT03585400 · ClinicalTrials.gov registry record
Validation of the REPS Prediction Tool
A clinical trial of Postoperative Respiratory Complication and Residual Neuromuscular Blockade, sponsored by Beth Israel Deaconess Medical Center.
- Completed
- Registry status
- 101,510
- Enrollment target
- 1
- Study location
NCT03585400: Completed study of Postoperative Respiratory Complication and Residual Neuromuscular Blockade, sponsored by Beth Israel Deaconess Medical Center.
NCT03585400 is a study of Postoperative Respiratory Complication and Residual Neuromuscular Blockade that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 101,510 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03585400, a study of Postoperative Respiratory Complication and Residual Neuromuscular Blockade, has completed, sponsored by Beth Israel Deaconess Medical Center.
- COMPLETED
- Registry status
- 101,510 participants
- Enrollment target
- 1
- Study location
Study Summary
Neuromuscular blocking agents' (NMBA) use during surgery is associated with postoperative respiratory complications and increased risk of readmission to the hospital following ambulatory surgery. Residual neuromuscular block (rNMB) after surgery is difficult to identify. We have recently developed the REsidual neuromuscular block Prediction Score (REPS), that predicts the risk for postoperative rNMB. Our primary objective is now to assess the predictive ability of the REPS for respiratory complications within seven days following general anaesthesia. The secondary objective is to compare the predictive values of REPS and train-of-four (TOF)-ratio below 0.90 for respiratory complications.
Primary Outcome
PRC composite of invasive mechanical ventilation requirement within 7 postoperative days or immediate post-extubation desaturation (SpO2 \<90%) within 10 minutes.
Conditions Studied
Interventions
- OTHER Observational Study
Study Locations (1)
Massachusetts
- Beth Israel Deaconess Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 101,510 participants |
| Start Date | 2018-06-29 |
| Est. Completion | 2020-12-31 |
What the finished NCT03585400 record still lists
NCT03585400 is an observational study that tracks outcomes without assigning an intervention. Its 101,510 participants enrollment target places it among the larger protocols in the corpus.
The record links to 3 conditions, with Postoperative Respiratory Complication appearing as the primary indexed condition, and to 1 intervention - of which Observational Study is the first listed.
NCT03585400 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03585400 about?
NCT03585400 is a clinical study titled "Validation of the REPS Prediction Tool". Neuromuscular blocking agents' (NMBA) use during surgery is associated with postoperative respiratory complications and increased risk of readmission to the hospital following ambulatory surgery. Residual neuromuscular block (rNMB) after surgery is difficult to identify. We have recently developed t...
What is the current status of trial NCT03585400?
This trial is currently completed. The enrollment target is 101,510 participants. The study started on 2018-06-29. Estimated completion is 2020-12-31.
What conditions does trial NCT03585400 study?
This clinical trial studies the following conditions: Postoperative Respiratory Complication, Residual Neuromuscular Blockade, Curarization, Postoperative Residual.
What interventions are being tested in trial NCT03585400?
The interventions under investigation include: Observational Study (OTHER).
Who is sponsoring clinical trial NCT03585400?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03585400 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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