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NCT03576768 · ClinicalTrials.gov registry record · NA
QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt
A NA study, sponsored by Medical University of South Carolina.
- Terminated
- Registry status
- NA
- Development phase
- 25
- Enrollment target
NCT03576768: Clinical Trial NA study, sponsored by Medical University of South Carolina.
NCT03576768 is a NA study that was terminated before completion, run by Medical University of South Carolina. The registered enrollment target is 25 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03576768, a NA study, was terminated before completion, sponsored by Medical University of South Carolina.
- TERMINATED
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
Study Summary
Cigarette smoking constitutes the greatest preventable cause of mortality and morbidity in the US. The most critical period for long term success of smoking cessation appears to be in the first 7 days after the quit date. A metaanalysis of 3 pharmacotherapy trials revealed that abstinence during the first 7 days was the strongest predictor of 6 month outcomes (n=1649; Odds ratio: 1.4, P \<0.0001; Ashare et al. 2013). Prodigious relapse rates during this first week of smoking cessation are likely due to behavioral and neurobiological factors that contribute to high cue-associated craving and low executive control over smoking. The long term goal of the research is to develop evidence-based transcranial magnetic stimulation protocols to facilitate abstinence during this critical period.
Primary Outcome
The Fagerstrom Test for Nicotine Dependence will be measured at Visit 1 and after 10 days of treatment (Visit 10). In scoring the Fagerstrom Test for Nicotine Dependence, yes/no items are scored from 0 to 1 and multiple-choice items are scored from 0 to 3. The items are summed to yield a total score of 0-10. The higher the total Fagerstrom score, the more intense is the patient's physical dependence on nicotine. .For this outcome we will measure the difference in the score for those that complet
Interventions
- DEVICE Sham cTBS
- DEVICE Sham iTBS
- DEVICE Real iTBS
- DEVICE Real cTBS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2018-09-04 |
| Est. Completion | 2019-10-25 |
| Phase | NA |
Why NCT03576768 stopped before completion
NCT03576768 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 4 interventions - of which Sham cTBS is the first listed.
NCT03576768 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03576768 about?
NCT03576768 is a clinical study titled "QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt". Cigarette smoking constitutes the greatest preventable cause of mortality and morbidity in the US. The most critical period for long term success of smoking cessation appears to be in the first 7 days after the quit date. A metaanalysis of 3 pharmacotherapy trials revealed that abstinence during the...
What is the current status of trial NCT03576768?
This trial is currently terminated. It is a NA study. The enrollment target is 25 participants. The study started on 2018-09-04. Estimated completion is 2019-10-25.
What interventions are being tested in trial NCT03576768?
The interventions under investigation include: Sham cTBS (DEVICE), Sham iTBS (DEVICE), Real iTBS (DEVICE), Real cTBS (DEVICE).
Who is sponsoring clinical trial NCT03576768?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03576768's enrollment target sits among peer trials
25 1712th of 2000 higher than 265 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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