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NCT03567837 · ClinicalTrials.gov registry record · NA
Fructose-induced Hepatic De Novo Lipogenesis in Adolescents With Obesity
A NA study, sponsored by The Rogosin Institute.
- Terminated
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT03567837 is a NA study that was terminated before completion, run by The Rogosin Institute. The registered enrollment target is 12 participants.
The verdict
NCT03567837, a NA study, was terminated before completion, sponsored by The Rogosin Institute.
- TERMINATED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
In the U.S., dietary fructose has increased in parallel with the increase in obesity and may promote the development of diabetes and other chronic diseases. The largest source of dietary fructose is sweetened beverages that are consumed by adolescents more than any other age group. This protocol will compare the rates of hepatic de novo lipogenesis (DNL), a process in the liver that changes sugar into fat, in two groups of obese adolescents - one with prediabetes and the other, metabolically healthy. Blood will be sampled before and hourly for 3 hours after the consumption of a fructose-containing beverage. We hypothesize that the pre-diabetic group will show greater DNL in response to fructose. This would support other evidence that increased fructose-induced hepatic DNL is an early mechanism linking dietary sugar to the adverse metabolic sequelae of obesity, including diabetes, fatty liver, dyslipidemia and coronary disease.
Interventions
- OTHER Fructose + Glucose Beverage
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2018-08-13 |
| Est. Completion | 2019-06-04 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03567837
The ClinicalTrials.gov registry entry for NCT03567837 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The Rogosin Institute, which has 21 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Fructose + Glucose Beverage is the first listed.
NCT03567837 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03567837 about?
NCT03567837 is a clinical study titled "Fructose-induced Hepatic De Novo Lipogenesis in Adolescents With Obesity". In the U.S., dietary fructose has increased in parallel with the increase in obesity and may promote the development of diabetes and other chronic diseases. The largest source of dietary fructose is sweetened beverages that are consumed by adolescents more than any other age group. This protocol wi...
What is the current status of trial NCT03567837?
This trial is currently terminated. It is a NA study. The enrollment target is 12 participants. The study started on 2018-08-13. Estimated completion is 2019-06-04.
What interventions are being tested in trial NCT03567837?
The interventions under investigation include: Fructose + Glucose Beverage (OTHER).
Who is sponsoring clinical trial NCT03567837?
This trial is sponsored by The Rogosin Institute, which has 21 total clinical trials registered on ClinicalTrials.gov.
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