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NCT03550885 · ClinicalTrials.gov registry record · NA
Diet Modulation of Bacterial Sulfur and Bile Acid Metabolism and Colon Cancer Risk
A NA study, sponsored by University of Illinois at Chicago.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT03550885 is a NA study that has completed, run by University of Illinois at Chicago. The registered enrollment target is 15 participants.
The verdict
NCT03550885, a NA study, has completed, sponsored by University of Illinois at Chicago.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
Determine in the context of a controlled crossover diet-intervention trial the role of taurocholic acid metabolism by gut bacteria in African American subjects at elevated risk for colorectal cancer (CRC). Two isocaloric diets, an animal-based diet high in taurine and saturated fat (HT-HSAT) and a plant-based, low in taurine and low saturated fat (LT-LSAT) will be used to determine the extent to which the relationship between diet (independent variable) and mucosal markers of CRC risk including epithelial proliferation, oxidative stress, DNA damage, and primary and secondary bile acid pools and biomarkers of inflammation (dependent variables) is explained by the abundance of sulfidogenic bacteria and hydrogen sulfide (H2S) concentrations \&/or deoxycholic acid (DCA) and DCA-producing bacteria clostridium scindens (mediator variables).
Interventions
- OTHER High taurine and saturated fat diet
- OTHER Low in taurine and saturated fat diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2018-08-01 |
| Est. Completion | 2021-12-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03550885
The ClinicalTrials.gov registry entry for NCT03550885 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Illinois at Chicago, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which High taurine and saturated fat diet is the first listed.
NCT03550885 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03550885 about?
NCT03550885 is a clinical study titled "Diet Modulation of Bacterial Sulfur and Bile Acid Metabolism and Colon Cancer Risk". Determine in the context of a controlled crossover diet-intervention trial the role of taurocholic acid metabolism by gut bacteria in African American subjects at elevated risk for colorectal cancer (CRC). Two isocaloric diets, an animal-based diet high in taurine and saturated fat (HT-HSAT) and a p...
What is the current status of trial NCT03550885?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2018-08-01. Estimated completion is 2021-12-01.
What interventions are being tested in trial NCT03550885?
The interventions under investigation include: High taurine and saturated fat diet (OTHER), Low in taurine and saturated fat diet (OTHER).
Who is sponsoring clinical trial NCT03550885?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
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