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Investigating Cabozantinib in Patients With Refractory Metastatic Colorectal Cancer
NCT03542877 · View on ClinicalTrials.gov ↗
Study Summary
This study seeks to use Cabozantinib to treat those with Metastatic Colorectal Cancer who have not previously responded to treatment.
Conditions Studied
Interventions
- DRUG Oral Tablet: Cabozantinib
Study Locations (10)
Pennsylvania
- Jefferson Abington Hospital — Abington
- Thomas Jefferson University — Philadelphia
- Fox Chase Cancer Center — Philadelphia
Colorado
- Universtiy of Colorado Denver — Aurora
- Lone Tree Health Center — Lone Tree
Arizona
- University of Arizona — Tucson
California
- Kenneth Norris Jr. Comprehensive Cancer Center — Los Angeles
Massachusetts
- Massachusetts General Hospital Cancer Center — Boston
New Jersey
- Rutgers Cancer Institute of New Jersey — New Brunswick
Washington
- Swedish Medical Center — Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2018-06-01 |
| Est. Completion | 2022-03-07 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03542877
The ClinicalTrials.gov registry entry for NCT03542877 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Academic Thoracic Oncology Medical Investigators Consortium, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention — of which Oral Tablet: Cabozantinib is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03542877 reports 10 study locations spanning 7 distinct geographic areas — top geographies include Pennsylvania, Colorado, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03542877 about?
NCT03542877 is a clinical study titled "Investigating Cabozantinib in Patients With Refractory Metastatic Colorectal Cancer". This study seeks to use Cabozantinib to treat those with Metastatic Colorectal Cancer who have not previously responded to treatment.
What is the current status of trial NCT03542877?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2018-06-01. Estimated completion is 2022-03-07.
What conditions does trial NCT03542877 study?
This clinical trial studies the following conditions: Colorectal Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03542877?
The interventions under investigation include: Oral Tablet: Cabozantinib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03542877?
This trial is sponsored by Academic Thoracic Oncology Medical Investigators Consortium, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03542877 being conducted?
This trial has 10 study locations across Arizona, California, Colorado, Massachusetts, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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