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NCT03539198 · ClinicalTrials.gov registry record

Study of Proton SBRT and Immunotherapy for Recurrent/Progressive Locoregional or Metastatic Head and Neck Cancer

A clinical trial, sponsored by Mayo Clinic.

Terminated
Registry status
19
Enrollment target

NCT03539198: Clinical Trial study, sponsored by Mayo Clinic.

NCT03539198 is a clinical trial that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 19 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03539198 was terminated before completion, sponsored by Mayo Clinic.

TERMINATED
Registry status
19 participants
Enrollment target

Study Summary

This study observes the clinical efficacy of combining proton SBRT with PD-1 blockade immunotherapy in both the locoregionally recurrent and metastatic settings.

Interventions

  • RADIATION Proton Stereotactic Body Radiation Therapy (SBRT) (5 fractions; 3500-4500 cGy)
  • RADIATION Proton Stereotactic Body Radiation Therapy (SBRT) (3-5 fractions; various dose and fractionation regimens depending on treatment site).
  • DRUG Nivolumab 3 mg/kg IV q2 weeks
  • RADIATION Proton or Photon SBRT (3-5 fractions; various dose and fractionation regimens depending on treatment site).

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2018-07-03
Est. Completion 2020-01-06

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT03539198

The ClinicalTrials.gov registry entry for NCT03539198 describes a study currently listed as terminated, categorized as an unspecified phase. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Proton Stereotactic Body Radiation Therapy (SBRT) (5 fractions; 3500-4500 cGy) is the first listed.

NCT03539198 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03539198 about?

NCT03539198 is a clinical study titled "Study of Proton SBRT and Immunotherapy for Recurrent/Progressive Locoregional or Metastatic Head and Neck Cancer". This study observes the clinical efficacy of combining proton SBRT with PD-1 blockade immunotherapy in both the locoregionally recurrent and metastatic settings.

What is the current status of trial NCT03539198?

This trial is currently terminated. The enrollment target is 19 participants. The study started on 2018-07-03. Estimated completion is 2020-01-06.

What interventions are being tested in trial NCT03539198?

The interventions under investigation include: Proton Stereotactic Body Radiation Therapy (SBRT) (5 fractions; 3500-4500 cGy) (RADIATION), Proton Stereotactic Body Radiation Therapy (SBRT) (3-5 fractions; various dose and fractionation regimens depending on treatment site). (RADIATION), Nivolumab 3 mg/kg IV q2 weeks (DRUG), Proton or Photon SBRT (3-5 fractions; various dose and fractionation regimens depending on treatment site). (RADIATION).

Who is sponsoring clinical trial NCT03539198?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.