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NCT03534804 · ClinicalTrials.gov registry record · Phase 2

Cabozantinib Plus Pembrolizumab as First-Line Therapy for Cisplatin-Ineligible Advanced Urothelial Carcinoma

A Phase 2 study, sponsored by University of Utah.

Completed
Registry status
Phase 2
Development phase
37
Enrollment target

NCT03534804 is a Phase 2 study that has completed, run by University of Utah. The registered enrollment target is 37 participants.

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The verdict

NCT03534804, a Phase 2 study, has completed, sponsored by University of Utah.

COMPLETED
Registry status
Phase 2
Development phase
37 participants
Enrollment target

Study Summary

This is an open label, non-randomized phase 2 study of the combination of pembrolizumab and cabozantinib to assess overall response rate (ORR), progression free survival at 6 months (PFS6), and overall survival (OS) in patients with metastatic urothelial carcinoma (UC) ineligible for cisplatin.

Interventions

  • DRUG Pembrolizumab
  • DRUG Cabozantinib

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2018-09-18
Est. Completion 2024-04-15
Phase Phase 2

Sponsor

University of Utah

818 total trials

What the Registry Record Tells You About NCT03534804

The ClinicalTrials.gov registry entry for NCT03534804 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT03534804 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03534804 about?

NCT03534804 is a clinical study titled "Cabozantinib Plus Pembrolizumab as First-Line Therapy for Cisplatin-Ineligible Advanced Urothelial Carcinoma". This is an open label, non-randomized phase 2 study of the combination of pembrolizumab and cabozantinib to assess overall response rate (ORR), progression free survival at 6 months (PFS6), and overall survival (OS) in patients with metastatic urothelial carcinoma (UC) ineligible for cisplatin.

What is the current status of trial NCT03534804?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 37 participants. The study started on 2018-09-18. Estimated completion is 2024-04-15.

What interventions are being tested in trial NCT03534804?

The interventions under investigation include: Pembrolizumab (DRUG), Cabozantinib (DRUG).

Who is sponsoring clinical trial NCT03534804?

This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.