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NCT03534063 · ClinicalTrials.gov registry record · NA
Implementing Genomics in Practice (IGNITE): CYP2D6 Genotype-Guided Pain Management in Patients Undergoing Arthroplasty Surgery
A NA study, sponsored by University of Florida.
- Completed
- Registry status
- NA
- Development phase
- 260
- Enrollment target
NCT03534063: Completed NA study, sponsored by University of Florida.
NCT03534063 is a NA study that has completed, run by University of Florida. The registered enrollment target is 260 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03534063, a NA study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 260 participants
- Enrollment target
Study Summary
This will be a randomized, open-labeled pilot pragmatic clinical trial. Patients undergoing arthroplasty surgery will be recruited from the University of Florida (UF) Health Gainesville and the Villages Orthopedic clinics for CYP2D6 pharmacogenetic testing to manage post-surgical pain. Patients will be randomized 2:1 to either usual care or genotype-guided care. The aims of the study were to: 1) test the feasibility of a genotype-guided opioid prescribing approach for patients undergoing an outpatient surgical procedure, a group at high risk for persistent opioid use; and 2) evaluate the effect of genotype-guided post-surgical pain management on pain control and opioid prescribing.
Primary Outcome
The feasibility of clinical implementation was measured by the percentage of approached patients who agreed to be the study. This was measured by the number of patients approached and the number of patients who enrolled in the study.
Interventions
- GENETIC CYP2D6-guided opioid therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 260 participants |
| Start Date | 2018-06-07 |
| Est. Completion | 2020-04-29 |
| Phase | NA |
What the finished NCT03534063 record still lists
NCT03534063 is an interventional study that assigns participants to a tested intervention. The registered 260 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 1 intervention - of which CYP2D6-guided opioid therapy is the first listed.
NCT03534063 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03534063 about?
NCT03534063 is a clinical study titled "Implementing Genomics in Practice (IGNITE): CYP2D6 Genotype-Guided Pain Management in Patients Undergoing Arthroplasty Surgery". This will be a randomized, open-labeled pilot pragmatic clinical trial. Patients undergoing arthroplasty surgery will be recruited from the University of Florida (UF) Health Gainesville and the Villages Orthopedic clinics for CYP2D6 pharmacogenetic testing to manage post-surgical pain. Patients will...
What is the current status of trial NCT03534063?
This trial is currently completed. It is a NA study. The enrollment target is 260 participants. The study started on 2018-06-07. Estimated completion is 2020-04-29.
What interventions are being tested in trial NCT03534063?
The interventions under investigation include: CYP2D6-guided opioid therapy (GENETIC).
Who is sponsoring clinical trial NCT03534063?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03534063's enrollment target sits among peer trials
260 397th of 2000 higher than 1,601 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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