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NCT03526146 · ClinicalTrials.gov registry record · NA

Preventing Loss of Independence Through Exercise (PLIÉ) in Persons With Mild Cognitive Impairment (MCI)

A NA study of Mild Cognitive Impairment, sponsored by University of California, San Francisco.

Completed
Registry status
NA
Development phase
41
Enrollment target
1
Study location

NCT03526146 is a NA study of Mild Cognitive Impairment that has completed, run by University of California, San Francisco. The registered enrollment target is 41 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03526146, a NA study of Mild Cognitive Impairment, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
NA
Development phase
41 participants
Enrollment target
1
Study location

Study Summary

Nearly 1 in 10 older Americans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status. Mild cognitive impairment (MCI) is an intermediate stage between the expected cognitive decline of normal aging and the more-serious decline of dementia. The investigators have developed a novel, integrative exercise program called Preventing Loss of Independence through Exercise (PLIE) that incorporates elements from Eastern and Western exercise modalities and is designed to build and maintain the capacity to perform basic functional movements while increasing mindful body awareness and enhancing social connection. Pilot study results suggest that PLIE is associated with meaningful improvements in physical function, cognitive function and quality of life in individuals with dementia, as well as reduced caregiver burden. The goal of the current study is to perform a randomized, controlled trial to test the efficacy of PLIE in older adults who have MCI but who do not yet have dementia. The investigators will also investigate the neural mechanisms underlying PLIE by acquiring brain imaging measures.

Conditions Studied

Interventions

  • BEHAVIORAL Behavioral: Preventing Loss of Independence through Exercise (PLIE)

Study Locations (1)

California

  • San Francisco VA Medical Center, San Francisco, CA - San Francisco

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2018-08-30
Est. Completion 2020-10-30
Phase NA

What the Registry Record Tells You About NCT03526146

The ClinicalTrials.gov registry entry for NCT03526146 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (97% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 1 intervention - of which Behavioral: Preventing Loss of Independence through Exercise (PLIE) is the first listed.

NCT03526146 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03526146 about?

NCT03526146 is a clinical study titled "Preventing Loss of Independence Through Exercise (PLIÉ) in Persons With Mild Cognitive Impairment (MCI)". Nearly 1 in 10 older Americans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status. Mild cognitive impairment (MCI) is an intermediate stage between the expected cognitive decline of normal aging and the more-serious decline of demen...

What is the current status of trial NCT03526146?

This trial is currently completed. It is a NA study. The enrollment target is 41 participants. The study started on 2018-08-30. Estimated completion is 2020-10-30.

What conditions does trial NCT03526146 study?

This clinical trial studies the following conditions: Mild Cognitive Impairment.

What interventions are being tested in trial NCT03526146?

The interventions under investigation include: Behavioral: Preventing Loss of Independence through Exercise (PLIE) (BEHAVIORAL).

Who is sponsoring clinical trial NCT03526146?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03526146 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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