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NCT03518294 · ClinicalTrials.gov registry record · NA
NASH Fitness Intervention in Thrombosis Trial (NASHFit)
A NA study, sponsored by Milton S. Hershey Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 28
- Enrollment target
NCT03518294: Completed NA study, sponsored by Milton S. Hershey Medical Center.
NCT03518294 is a NA study that has completed, run by Milton S. Hershey Medical Center. The registered enrollment target is 28 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03518294, a NA study, has completed, sponsored by Milton S. Hershey Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 28 participants
- Enrollment target
Study Summary
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in the United States. The most advanced forms of NAFLD are associated with increased liver-related mortality and lower overall survival. The current standard of care for NAFLD is lifestyle changes through diet and exercise. The human genome and regulation of gene expression is influenced by physical activity. NAFLD is a prothrombotic state with derangements in all three phases of hemostasis leading to clinically important clotting events. Exercise can improve coagulation in healthy persons. In this proposal, we seek to begin a line of work to answer the question "Can lifestyle changes effectively mitigate the increased risk of clotting in patients with NAFLD?" focusing initially on the at-risk population genetically susceptible to advanced disease.
Primary Outcome
Change in fibrinolysis as indicated by PAI-1 level was calculated by taking the difference of measurements at baseline and 5 months.
Interventions
- BEHAVIORAL Aerobic Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2018-06-01 |
| Est. Completion | 2021-03-24 |
| Phase | NA |
What the finished NCT03518294 record still lists
NCT03518294 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Aerobic Exercise is the first listed.
NCT03518294 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03518294 about?
NCT03518294 is a clinical study titled "NASH Fitness Intervention in Thrombosis Trial (NASHFit)". Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in the United States. The most advanced forms of NAFLD are associated with increased liver-related mortality and lower overall survival. The current standard of care for NAFLD is lifestyle changes through diet and...
What is the current status of trial NCT03518294?
This trial is currently completed. It is a NA study. The enrollment target is 28 participants. The study started on 2018-06-01. Estimated completion is 2021-03-24.
What interventions are being tested in trial NCT03518294?
The interventions under investigation include: Aerobic Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT03518294?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03518294's enrollment target sits among peer trials
28 1704th of 2000 higher than 293 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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