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NCT03517293 · ClinicalTrials.gov registry record · NA
Enhanced Neonatal Health and Neonatal Cardiac Effect Developmentally
A NA study, sponsored by East Carolina University.
- Completed
- Registry status
- NA
- Development phase
- 133
- Enrollment target
NCT03517293 is a NA study that has completed, run by East Carolina University. The registered enrollment target is 133 participants.
The verdict
NCT03517293, a NA study, has completed, sponsored by East Carolina University.
- COMPLETED
- Registry status
- NA
- Development phase
- 133 participants
- Enrollment target
Study Summary
AHA and ACSM recognize lack of exercise is a major risk factor for developing cardiovascular disease (CVD), and other CVD risk factors such as obesity. It is important to note that CVD is the sixth leading cause of death and children are more likely to be undiagnosed due to their age and lack of symptoms. Further, according to the CDC, over one-third of children and adolescents are overweight or obese and at increased risk of CVD. Although many programs for children aim to decrease CVD risks and obesity few, if any, programs begin the intervention during prenatal development. Our preliminary findings suggest that regular maternal exercise improves cardiovascular health (lower heart rate, increased heart rate variability), normalizes body fat composition, and improves nervous system and motor tone even after birth. Norepinephrine is essential for fetal development, influences many tissues (heart, nerve cells, skeletal muscle, and fat cells), and can stimulate growth factors. It is believed that exercise hormones, such as norepinephrine, released during maternal exercise influence these growth factors during development. The central hypothesis of this proposal is that regular maternal exercise during pregnancy will improve the health of offspring before and after birth as evidenced by lower resting heart rate, increasing heart rate variability improved neurological maturation, and decreased adiposity. We have three specific aims to test this hypothesis through the Enhanced Neonatal Health and Neonatal Cardiovascular Efficiency Developmentally (ENHANCED) by Mom project (IRB approved #12-002524). Aim 1 will establish the association between maternal exercise during pregnancy and the heart health of offspring before and after birth. Aim 2 will determine the relationship between modes of regular maternal exercise and neonate neurological and muscular maturation as this relates to health of the child after birth. Aim 3 will elucidate the influence of different modes of ma
Interventions
- BEHAVIORAL Aerobic Exercise training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 133 participants |
| Start Date | 2015-07-01 |
| Est. Completion | 2023-01-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03517293
The ClinicalTrials.gov registry entry for NCT03517293 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 133 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is East Carolina University, which has 58 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Aerobic Exercise training is the first listed.
NCT03517293 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03517293 about?
NCT03517293 is a clinical study titled "Enhanced Neonatal Health and Neonatal Cardiac Effect Developmentally". AHA and ACSM recognize lack of exercise is a major risk factor for developing cardiovascular disease (CVD), and other CVD risk factors such as obesity. It is important to note that CVD is the sixth leading cause of death and children are more likely to be undiagnosed due to their age and lack of sym...
What is the current status of trial NCT03517293?
This trial is currently completed. It is a NA study. The enrollment target is 133 participants. The study started on 2015-07-01. Estimated completion is 2023-01-30.
What interventions are being tested in trial NCT03517293?
The interventions under investigation include: Aerobic Exercise training (BEHAVIORAL).
Who is sponsoring clinical trial NCT03517293?
This trial is sponsored by East Carolina University, which has 58 total clinical trials registered on ClinicalTrials.gov.
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