Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03514407 · ClinicalTrials.gov registry record · Phase 1

A Study of INCB059872 in Relapsed or Refractory Ewing Sarcoma

A Phase 1 study, sponsored by Incyte Corporation.

Terminated
Registry status
Phase 1
Development phase
25
Enrollment target

NCT03514407: Clinical Trial Phase 1 study, sponsored by Incyte Corporation.

NCT03514407 is a Phase 1 study that was terminated before completion, run by Incyte Corporation. The registered enrollment target is 25 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03514407, a Phase 1 study, was terminated before completion, sponsored by Incyte Corporation.

TERMINATED
Registry status
Phase 1
Development phase
25 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and preliminary antitumor activity of INCB059872 in participants with Ewing sarcoma who are refractory or relapsed from prior standard therapy and not eligible for further standard systemic therapy.

Primary Outcome

Defined as any untoward medical occurrence in a participant or clinical study participant, temporally associated with the use of a drug in humans, whether or not considered drug-related.

Interventions

  • DRUG INCB059872

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2018-06-27
Est. Completion 2020-06-25
Phase Phase 1
Incyte Corporation

239 total trials

Why NCT03514407 stopped before completion

NCT03514407 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower).

The record links to 0 conditions, and to 1 intervention - of which INCB059872 is the first listed.

NCT03514407 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03514407 about?

NCT03514407 is a clinical study titled "A Study of INCB059872 in Relapsed or Refractory Ewing Sarcoma". The purpose of this study is to evaluate the safety and preliminary antitumor activity of INCB059872 in participants with Ewing sarcoma who are refractory or relapsed from prior standard therapy and not eligible for further standard systemic therapy.

What is the current status of trial NCT03514407?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2018-06-27. Estimated completion is 2020-06-25.

What interventions are being tested in trial NCT03514407?

The interventions under investigation include: INCB059872 (DRUG).

Who is sponsoring clinical trial NCT03514407?

This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03514407's enrollment target sits among peer trials

25 1495th of 2000 higher than 481 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01166854 · 25 participants

    Characterization of Familial Myopathy and Paget Disease of Bone

  • NCT01913106 · 25 participants · Phase 1

    HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer

  • NCT02138669 · 25 participants · NA

    Intacs Prescription Inserts for Keratoconus Patients

  • NCT02174549 · 25 participants · Phase 1

    Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03514407, the US trial registry maintained by the National Library of Medicine. NCT03514407 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.