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NCT03509012 · ClinicalTrials.gov registry record · Phase 1

Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors

A Phase 1 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 1
Development phase
105
Enrollment target

NCT03509012 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 105 participants.

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The verdict

NCT03509012, a Phase 1 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 1
Development phase
105 participants
Enrollment target

Study Summary

This is an open-label, multicenter, phase I study to evaluate the safety and tolerability of durvalumab ± tremelimumab in combination with chemoradiation in patients with advanced solid tumors

Interventions

  • DRUG Durvalumab
  • DRUG Tremelimumab
  • DRUG Cisplatin (dose level 4)
  • DRUG Cisplatin (dose level 3)
  • DRUG Carboplatin (dose level 1)

Trial Details

FieldValue
Enrollment Target 105 participants
Start Date 2018-05-02
Est. Completion 2025-01-08
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT03509012

The ClinicalTrials.gov registry entry for NCT03509012 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 105 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Durvalumab is the first listed.

NCT03509012 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03509012 about?

NCT03509012 is a clinical study titled "Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors". This is an open-label, multicenter, phase I study to evaluate the safety and tolerability of durvalumab ± tremelimumab in combination with chemoradiation in patients with advanced solid tumors

What is the current status of trial NCT03509012?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 105 participants. The study started on 2018-05-02. Estimated completion is 2025-01-08.

What interventions are being tested in trial NCT03509012?

The interventions under investigation include: Durvalumab (DRUG), Tremelimumab (DRUG), Cisplatin (dose level 4) (DRUG), Cisplatin (dose level 3) (DRUG), Carboplatin (dose level 1) (DRUG).

Who is sponsoring clinical trial NCT03509012?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.