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NCT03491176 · ClinicalTrials.gov registry record
Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer
A clinical trial of Head and Neck Cancer and Healthy Subject, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT03491176: Active study of Head and Neck Cancer and Healthy Subject, sponsored by M.D. Anderson Cancer Center.
NCT03491176 is a study of Head and Neck Cancer and Healthy Subject that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 100 participants, below the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03491176, a study of Head and Neck Cancer and Healthy Subject, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this research study is to find out if using additional MRIs and biomarker testing can help researchers learn to predict how the tumor may change during radiation therapy. Biomarkers are found in the blood/tissue and may be related to participant's reaction to treatment. Biomarker testing in the study may include genetic biomarkers. This is an investigational study. MRIs on this study are performed using FDA-approved and commercially available methods. Having added scans and blood tests is investigational. Up to 100 participants will be enrolled in this study (up to 80 patients and up to 20 healthy volunteers in another part of the study). All will take part at MD Anderson.
Primary Outcome
TGV is the calculated daily increase in tumor size from diagnosis to immediately before first radiotherapy (RT) treatment as measured via magnetic resonance imaging (MRI). Will use graphs and descriptive statistics to evaluate the relationship between TGV, tumor kinetics (TK), and circulating tumor cells (CTCs) with response.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Quality-of-Life Assessment
- PROCEDURE Magnetic Resonance Imaging
- OTHER Questionnaire Administration
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2017-05-18 |
| Est. Completion | 2027-10-31 |
What the registry record for NCT03491176 still lists
NCT03491176 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (62% lower).
The record links to 3 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 4 interventions - of which Biospecimen Collection is the first listed.
NCT03491176 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT03491176 about?
NCT03491176 is a clinical study titled "Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer". The goal of this research study is to find out if using additional MRIs and biomarker testing can help researchers learn to predict how the tumor may change during radiation therapy. Biomarkers are found in the blood/tissue and may be related to participant's reaction to treatment. Biomarker testin...
What is the current status of trial NCT03491176?
This trial is currently active not recruiting. The enrollment target is 100 participants. The study started on 2017-05-18. Estimated completion is 2027-10-31.
What conditions does trial NCT03491176 study?
This clinical trial studies the following conditions: Head and Neck Cancer, Healthy Subject, Cutaneous Squamous Cell Carcinoma of the Head and Neck.
What interventions are being tested in trial NCT03491176?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Quality-of-Life Assessment (OTHER), Magnetic Resonance Imaging (PROCEDURE), Questionnaire Administration (OTHER).
Who is sponsoring clinical trial NCT03491176?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03491176 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03491176's enrollment target sits among peer trials
100 82nd of 250 higher than 165 of 250 other Head and Neck Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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