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NCT03489421 · ClinicalTrials.gov registry record
Mitochondria in HIV and Aging (MITO+)
A clinical trial, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- 14
- Enrollment target
NCT03489421: Completed study, sponsored by University of Colorado, Denver.
NCT03489421 is a clinical trial that has completed, run by University of Colorado, Denver. The registered enrollment target is 14 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03489421 has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- 14 participants
- Enrollment target
Study Summary
Older adults with human immunodeficiency virus (HIV) and a long history of antiretroviral therapy have more mitochondrial dysfunction- the cells that help them make energy. This dysfunction in mitochondria may lead to symptoms of muscle fatigue, physical function impairment, and impaired exercise tolerance compared to HIV-uninfected controls of a similar age and body mass index (BMI). Furthermore, the investigators hypothesize that the older antiretroviral therapy (ART) of tenofovir disoproxil fumarate (TDF) is associated with greater impairment in mitochondrial function than the newer agent, tenofovir alafenamide (TAF).
Primary Outcome
ADP/ATP ratio between HIV-infected and uninfected subjects
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2018-12-15 |
| Est. Completion | 2019-09-05 |
What the finished NCT03489421 record still lists
NCT03489421 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 14 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT03489421 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03489421 about?
NCT03489421 is a clinical study titled "Mitochondria in HIV and Aging (MITO+)". Older adults with human immunodeficiency virus (HIV) and a long history of antiretroviral therapy have more mitochondrial dysfunction- the cells that help them make energy. This dysfunction in mitochondria may lead to symptoms of muscle fatigue, physical function impairment, and impaired exercise to...
What is the current status of trial NCT03489421?
This trial is currently completed. The enrollment target is 14 participants. The study started on 2018-12-15. Estimated completion is 2019-09-05.
Who is sponsoring clinical trial NCT03489421?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
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