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NCT03484923 · ClinicalTrials.gov registry record · Phase 2
Study of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma
A Phase 2 study of Melanoma, sponsored by Novartis Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 196
- Enrollment target
- 20
- Study locations
NCT03484923 is a Phase 2 study of Melanoma that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 196 participants, below the 706-participant average among 266 other Melanoma trials with a reported enrollment target (72% lower). The trial reports 20 study locations across 10 states.
The verdict
NCT03484923, a Phase 2 study of Melanoma, has completed, sponsored by Novartis Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 196 participants
- Enrollment target
- 20
- Study locations
Study Summary
The primary purpose of this study is to evaluate the efficacy of novel spartalizumab (PDR001) combinations in previously treated unresectable or metastatic melanoma
Conditions Studied
Interventions
- DRUG LEE011
- DRUG PDR001
- DRUG INC280
- DRUG LAG525
- DRUG ACZ885
Study Locations (20)
Other
- Novartis Investigative Site - Marseille
- Novartis Investigative Site - Paris
- Novartis Investigative Site - Villejuif
- Novartis Investigative Site - Dresden
- Novartis Investigative Site - Essen
- Novartis Investigative Site - Hamburg
- Novartis Investigative Site - Kiel
- Novartis Investigative Site - München
California
- The Angeles Clinic and Research Institute - Los Angeles
- University of California Los Angeles - Los Angeles
- UCSF Medical Center . - San Francisco
New South Wales
- Novartis Investigative Site - North Sydney
- Novartis Investigative Site - Westmead
Massachusetts
- Massachusetts General Hospital Massachusetts Gen. Hospital CC - Boston
New York
- NYU Laura and Isaac Perlmutter Cancer Center Perlmutter Cancer Center - New York
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Ontario
- Novartis Investigative Site - Toronto
Quebec
- Novartis Investigative Site - Montreal
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 196 participants |
| Start Date | 2018-09-10 |
| Est. Completion | 2022-12-30 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03484923
The ClinicalTrials.gov registry entry for NCT03484923 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 196 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 706-participant average among 266 other Melanoma trials with a reported enrollment target (72% lower). The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Melanoma appearing as the primary indexed condition, and to 5 interventions - of which LEE011 is the first listed.
NCT03484923 reports 20 study locations spanning 10 distinct geographic areas - top geographies include Other, California, New South Wales.
Frequently Asked Questions
What is clinical trial NCT03484923 about?
NCT03484923 is a clinical study titled "Study of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma". The primary purpose of this study is to evaluate the efficacy of novel spartalizumab (PDR001) combinations in previously treated unresectable or metastatic melanoma
What is the current status of trial NCT03484923?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 196 participants. The study started on 2018-09-10. Estimated completion is 2022-12-30.
What conditions does trial NCT03484923 study?
This clinical trial studies the following conditions: Melanoma.
What interventions are being tested in trial NCT03484923?
The interventions under investigation include: LEE011 (DRUG), PDR001 (DRUG), INC280 (DRUG), LAG525 (DRUG), ACZ885 (DRUG).
Who is sponsoring clinical trial NCT03484923?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03484923 being conducted?
This trial has 20 study locations across California, Massachusetts, New York, Pennsylvania, New South Wales. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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