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NCT03471182 · ClinicalTrials.gov registry record · Phase 1

Investigation of Cocaine Addiction Using mGluR5 PET and fMRI

A Phase 1 study, sponsored by Yale University.

Completed
Registry status
Phase 1
Development phase
32
Enrollment target

NCT03471182 is a Phase 1 study that has completed, run by Yale University. The registered enrollment target is 32 participants.

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The verdict

NCT03471182, a Phase 1 study, has completed, sponsored by Yale University.

COMPLETED
Registry status
Phase 1
Development phase
32 participants
Enrollment target

Study Summary

The proposed research program will investigate the changes in brain chemistry and circuitry that 're-wire' the brain during chronic cocaine use, promote relapse, and complicate treatment efforts. Currently-using and non-treatment-seeking individuals with a cocaine use disorder will undergo a cocaine self-administration paradigm 2-5 days prior to completing positron emission tomography (PET) and functional magnetic resonance imaging (fMRI).

Interventions

  • RADIATION Positron Emission Tomography
  • OTHER Magnetic Resonance Imaging
  • BEHAVIORAL Psychiatric and Cognitive Testing
  • DRUG Cocaine Self-adminstration

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2018-02-26
Est. Completion 2022-08-18
Phase Phase 1

Sponsor

Yale University

1,492 total trials

What the Registry Record Tells You About NCT03471182

The ClinicalTrials.gov registry entry for NCT03471182 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Positron Emission Tomography is the first listed.

NCT03471182 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03471182 about?

NCT03471182 is a clinical study titled "Investigation of Cocaine Addiction Using mGluR5 PET and fMRI". The proposed research program will investigate the changes in brain chemistry and circuitry that 're-wire' the brain during chronic cocaine use, promote relapse, and complicate treatment efforts. Currently-using and non-treatment-seeking individuals with a cocaine use disorder will undergo a cocaine...

What is the current status of trial NCT03471182?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2018-02-26. Estimated completion is 2022-08-18.

What interventions are being tested in trial NCT03471182?

The interventions under investigation include: Positron Emission Tomography (RADIATION), Magnetic Resonance Imaging (OTHER), Psychiatric and Cognitive Testing (BEHAVIORAL), Cocaine Self-adminstration (DRUG).

Who is sponsoring clinical trial NCT03471182?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.