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NCT03466736 · ClinicalTrials.gov registry record
Enriching Clinical Trials Requiring Amyloid Positivity With Practice Effects
A clinical trial of Alzheimer Disease and Mild Cognitive Impairment, sponsored by University of Utah.
- Completed
- Registry status
- 165
- Enrollment target
- 1
- Study location
NCT03466736: Completed study of Alzheimer Disease and Mild Cognitive Impairment, sponsored by University of Utah.
NCT03466736 is a study of Alzheimer Disease and Mild Cognitive Impairment that has completed, run by University of Utah. The registered enrollment target is 165 participants, below the 2,750-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03466736, a study of Alzheimer Disease and Mild Cognitive Impairment, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- 165 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective of this study is to demonstrate that individuals with low short-term practice effects (STPE) on cognitive testing are more likely to be identified as "positive" on amyloid imaging than individuals with high STPE. STPE may also inform us about other AD-related biomarkers, including hippocampal volumes, functional connectivity, and APOE status. By realizing the aims of this pragmatic study, we hope to be able to offer more economical and efficient screening of potential participants for clinical trials, which would reduce participant burden and financial costs.
Primary Outcome
Amount of improvement when cognitive tests are repeated twice within one week
Conditions Studied
Interventions
- DIAGNOSTIC_TEST [18F]flutemetamol PET scan
Study Locations (1)
Utah
- University of Utah - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 165 participants |
| Start Date | 2018-09-01 |
| Est. Completion | 2023-04-20 |
What the finished NCT03466736 record still lists
NCT03466736 is an observational study that tracks outcomes without assigning an intervention. The registered 165 participants enrollment target is mid-sized for trials with a published cap, below the 2,750-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (94% lower).
The record links to 2 conditions, with Alzheimer Disease appearing as the primary indexed condition, and to 1 intervention - of which [18F]flutemetamol PET scan is the first listed.
NCT03466736 reports a single indexed study location in Utah.
Frequently Asked Questions
What is clinical trial NCT03466736 about?
NCT03466736 is a clinical study titled "Enriching Clinical Trials Requiring Amyloid Positivity With Practice Effects". The primary objective of this study is to demonstrate that individuals with low short-term practice effects (STPE) on cognitive testing are more likely to be identified as "positive" on amyloid imaging than individuals with high STPE. STPE may also inform us about other AD-related biomarkers, includ...
What is the current status of trial NCT03466736?
This trial is currently completed. The enrollment target is 165 participants. The study started on 2018-09-01. Estimated completion is 2023-04-20.
What conditions does trial NCT03466736 study?
This clinical trial studies the following conditions: Alzheimer Disease, Mild Cognitive Impairment.
What interventions are being tested in trial NCT03466736?
The interventions under investigation include: [18F]flutemetamol PET scan (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03466736?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03466736 being conducted?
This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alzheimer Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03466736's enrollment target sits among peer trials
165 120th of 306 higher than 186 of 306 other Alzheimer Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alzheimer Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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