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NCT03463161 · ClinicalTrials.gov registry record · Phase 2
Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior Immunotherapy
A Phase 2 study, sponsored by University of Chicago.
- Terminated
- Registry status
- Phase 2
- Development phase
- 2
- Enrollment target
NCT03463161: Clinical Trial Phase 2 study, sponsored by University of Chicago.
NCT03463161 is a Phase 2 study that was terminated before completion, run by University of Chicago. The registered enrollment target is 2 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03463161, a Phase 2 study, was terminated before completion, sponsored by University of Chicago.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 2 participants
- Enrollment target
Study Summary
Study to determine response rate of the combination of pembrolizumab plus epacadostat in patients with head and neck cancers that have received prior immunotherapy.
Primary Outcome
Rate of clinical disease response (tumor shrinkage) as seen on imaging.
Interventions
- DRUG Pembrolizumab
- DRUG Epacadostat
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2018-03-23 |
| Est. Completion | 2018-12-04 |
| Phase | Phase 2 |
Why NCT03463161 stopped before completion
NCT03463161 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Pembrolizumab is the first listed.
NCT03463161 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03463161 about?
NCT03463161 is a clinical study titled "Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior Immunotherapy". Study to determine response rate of the combination of pembrolizumab plus epacadostat in patients with head and neck cancers that have received prior immunotherapy.
What is the current status of trial NCT03463161?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 2 participants. The study started on 2018-03-23. Estimated completion is 2018-12-04.
What interventions are being tested in trial NCT03463161?
The interventions under investigation include: Pembrolizumab (DRUG), Epacadostat (DRUG).
Who is sponsoring clinical trial NCT03463161?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03463161's enrollment target sits among peer trials
2 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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