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NCT03458494 · ClinicalTrials.gov registry record · NA
The TCF7L2 Gene: Dietary Prevention of T2DM
A NA study, sponsored by Tufts University.
- Terminated
- Registry status
- NA
- Development phase
- 37
- Enrollment target
NCT03458494 is a NA study that was terminated before completion, run by Tufts University. The registered enrollment target is 37 participants.
The verdict
NCT03458494, a NA study, was terminated before completion, sponsored by Tufts University.
- TERMINATED
- Registry status
- NA
- Development phase
- 37 participants
- Enrollment target
Study Summary
Nutrients and chemicals in food are able to regulate expression of genetic elements. Gene-nutrient interaction in response specific diets can increase an individual's risk, shifting the individual from health toward the development of chronic disease. The Transcription Factor 7 Like 2 (TCF7L2) gene may either put individuals at risk for or protect from Type 2 diabetes mellitus in the presence of certain foods. The main purpose of this four-week study is to examine diet-induced gene-nutrient interaction, with a focus on glucose, insulin, inflammation (CRP) and the plasma metabolome in individuals who have either the CC or the TT form of the rs7903146 single nucleotide polymorphism (SNP) (C/T) within the TCF7L2 gene. The (2) one-week study diets, one Mediterranean diet (MedDiet) based and the other low-fat based will be separated by a (1) week return to a regular habitual diet.
Interventions
- OTHER Mediterranean Diet
- OTHER Low-fat diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2018-02-15 |
| Est. Completion | 2020-04-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03458494
The ClinicalTrials.gov registry entry for NCT03458494 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Tufts University, which has 163 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Mediterranean Diet is the first listed.
NCT03458494 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03458494 about?
NCT03458494 is a clinical study titled "The TCF7L2 Gene: Dietary Prevention of T2DM". Nutrients and chemicals in food are able to regulate expression of genetic elements. Gene-nutrient interaction in response specific diets can increase an individual's risk, shifting the individual from health toward the development of chronic disease. The Transcription Factor 7 Like 2 (TCF7L2) gene ...
What is the current status of trial NCT03458494?
This trial is currently terminated. It is a NA study. The enrollment target is 37 participants. The study started on 2018-02-15. Estimated completion is 2020-04-30.
What interventions are being tested in trial NCT03458494?
The interventions under investigation include: Mediterranean Diet (OTHER), Low-fat diet (OTHER).
Who is sponsoring clinical trial NCT03458494?
This trial is sponsored by Tufts University, which has 163 total clinical trials registered on ClinicalTrials.gov.
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