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NCT03445689 · ClinicalTrials.gov registry record
Oxygenation Instability and Maturation of Control of Breathing in Premature Infants
A clinical trial, sponsored by University of Miami.
- Completed
- Registry status
- 70
- Enrollment target
NCT03445689: Completed study, sponsored by University of Miami.
NCT03445689 is a clinical trial that has completed, run by University of Miami. The registered enrollment target is 70 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03445689 has completed, sponsored by University of Miami.
- COMPLETED
- Registry status
- 70 participants
- Enrollment target
Study Summary
Premature infants present with significant oxygenation instability in the form of frequent spontaneous episodes of hypoxemia during the first weeks after birth. These infants are also exposed to hyperoxemia. The objective of this study is to determine the extent to which exposure to frequent episodes of hypoxemia and hyperoxemia in extreme premature infants during the early stages of their evolving lung disease is associated with altered maturation and function of their respiratory control system. This study is part of the Prematurity-Related Ventilatory Control (Pre-Vent): Role in Respiratory Outcomes Clinical Research Centers (CRC) (U01) cooperative program of the National Heart Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH).
Primary Outcome
Ventilatory response to oxygen (Dejours test)
Interventions
- OTHER Assessment of oxygenation instability
- OTHER Determination of mechanisms of hypoxemia episodes
- OTHER Assessment of respiratory instability
- OTHER apneic threshold of CO2
- OTHER Assessment of peripheral chemoreceptor function
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2018-09-04 |
| Est. Completion | 2023-11-01 |
What the finished NCT03445689 record still lists
NCT03445689 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 70 participants, a relatively small participant target.
The record links to 0 conditions, and to 5 interventions - of which Assessment of oxygenation instability is the first listed.
NCT03445689 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03445689 about?
NCT03445689 is a clinical study titled "Oxygenation Instability and Maturation of Control of Breathing in Premature Infants". Premature infants present with significant oxygenation instability in the form of frequent spontaneous episodes of hypoxemia during the first weeks after birth. These infants are also exposed to hyperoxemia. The objective of this study is to determine the extent to which exposure to frequent episod...
What is the current status of trial NCT03445689?
This trial is currently completed. The enrollment target is 70 participants. The study started on 2018-09-04. Estimated completion is 2023-11-01.
What interventions are being tested in trial NCT03445689?
The interventions under investigation include: Assessment of oxygenation instability (OTHER), Determination of mechanisms of hypoxemia episodes (OTHER), Assessment of respiratory instability (OTHER), apneic threshold of CO2 (OTHER), Assessment of peripheral chemoreceptor function (OTHER).
Who is sponsoring clinical trial NCT03445689?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
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