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NCT03428217 · ClinicalTrials.gov registry record · Phase 2

CANTATA: CB-839 With Cabozantinib vs. Cabozantinib With Placebo in Patients With Metastatic Renal Cell Carcinoma

A Phase 2 study, sponsored by Calithera Biosciences.

Completed
Registry status
Phase 2
Development phase
444
Enrollment target

NCT03428217 is a Phase 2 study that has completed, run by Calithera Biosciences. The registered enrollment target is 444 participants.

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The verdict

NCT03428217, a Phase 2 study, has completed, sponsored by Calithera Biosciences.

COMPLETED
Registry status
Phase 2
Development phase
444 participants
Enrollment target

Study Summary

Tthe primary objective of this study is to compare blinded Independent Radiology Committee (IRC)-adjudicated progression free survival (PFS) of patients treated with CB-839 + cabozantinib (CB-Cabo) versus placebo + cabozantinib (Pbo-Cabo) for advanced or metastatic clear-cell RCC (ccRCC).

Interventions

  • DRUG Placebo
  • DRUG Cabozantinib
  • DRUG CB-839

Trial Details

FieldValue
Enrollment Target 444 participants
Start Date 2018-04-24
Est. Completion 2021-07-16
Phase Phase 2

Sponsor

Calithera Biosciences

22 total trials

What the Registry Record Tells You About NCT03428217

The ClinicalTrials.gov registry entry for NCT03428217 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 444 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Calithera Biosciences, which has 22 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT03428217 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03428217 about?

NCT03428217 is a clinical study titled "CANTATA: CB-839 With Cabozantinib vs. Cabozantinib With Placebo in Patients With Metastatic Renal Cell Carcinoma". Tthe primary objective of this study is to compare blinded Independent Radiology Committee (IRC)-adjudicated progression free survival (PFS) of patients treated with CB-839 + cabozantinib (CB-Cabo) versus placebo + cabozantinib (Pbo-Cabo) for advanced or metastatic clear-cell RCC (ccRCC).

What is the current status of trial NCT03428217?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 444 participants. The study started on 2018-04-24. Estimated completion is 2021-07-16.

What interventions are being tested in trial NCT03428217?

The interventions under investigation include: Placebo (DRUG), Cabozantinib (DRUG), CB-839 (DRUG).

Who is sponsoring clinical trial NCT03428217?

This trial is sponsored by Calithera Biosciences, which has 22 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.