Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 3

Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)

NCT06700343 · View on ClinicalTrials.gov ↗

Study Summary

The main objectives of the study are to demonstrate pharmacokinetics (PK) similarity between ABP 692 and Ocrelizumab (US), and ABP 692 and Ocrelizumab (EU), and to demonstrate pharmacodynamics (PD) similarity between ABP 692 and Ocrelizumab reference product (RP) based on assessment of the suppression of new active brain lesions over 24 weeks as assessed by magnetic brain imaging (MRI).

Interventions

  • DRUG Ocrelizumab (US)
  • DRUG Ocrelizumab (EU)
  • DRUG ABP 692

Study Locations (20)

Florida

  • Neurology Offices of South Florida — Boca Raton
  • Aqualane Clinical Research — Naples
  • Knight Neurology — Rockledge
  • Premiere Research Institute Palm Beach — West Palm Beach

Colorado

  • Mountain Neurological Research Center — Basalt
  • Advanced Neurosciences Research, Llc — Fort Collins

Michigan

  • Henry Ford Health — Detroit
  • Michigan Institute For Neurological Disorders (Glendale Neurological Associates) - Farmington Hills — Farmington

New Jersey

  • JFK Medical Center — Edison
  • Hackensack Meridian Health — Paramus

Ohio

  • Singlepoint Healthcare Opco, LLC — Columbus
  • NDx Clinical Research, Inc — Dayton

Alabama

  • University of South Alabama — Mobile

Arizona

  • Clinical Endpoints, LLC — Scottsdale

California

  • Profound Research - Neurology Center of Southern California — Carlsbad

Trial Details

FieldValue
Enrollment Target 444 participants
Start Date 2025-01-13
Est. Completion 2027-12-17
Phase Phase 3

Sponsor

Amgen

266 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06700343

The ClinicalTrials.gov registry entry for NCT06700343 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 444 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 266 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Relapsing-remitting Multiple Sclerosis (RRMS) appearing as the primary indexed condition, and to 3 interventions — of which Ocrelizumab (US) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06700343 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Florida, Colorado, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06700343 about?

NCT06700343 is a clinical study titled "Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)". The main objectives of the study are to demonstrate pharmacokinetics (PK) similarity between ABP 692 and Ocrelizumab (US), and ABP 692 and Ocrelizumab (EU), and to demonstrate pharmacodynamics (PD) similarity between ABP 692 and Ocrelizumab reference product (RP) based on assessment of the suppressi...

What is the current status of trial NCT06700343?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 444 participants. The study started on 2025-01-13. Estimated completion is 2027-12-17.

What conditions does trial NCT06700343 study?

This clinical trial studies the following conditions: Relapsing-remitting Multiple Sclerosis (RRMS). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06700343?

The interventions under investigation include: Ocrelizumab (US) (DRUG), Ocrelizumab (EU) (DRUG), ABP 692 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06700343?

This trial is sponsored by Amgen, which has 266 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06700343 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial