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NCT03427424 · ClinicalTrials.gov registry record
Imaging Biomarker for Addiction Treatment Outcome
A clinical trial, sponsored by National Institute on Drug Abuse (NIDA).
- Terminated
- Registry status
- 52
- Enrollment target
NCT03427424 is a clinical trial that was terminated before completion, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 52 participants.
The verdict
NCT03427424 was terminated before completion, sponsored by National Institute on Drug Abuse (NIDA).
- TERMINATED
- Registry status
- 52 participants
- Enrollment target
Study Summary
Background: Many people suffer from drug addiction. But currently, treatments are not very effective. One group of patients in this study are enrolled in addiction treatment through physician health programs (PHPs). About 70% of these patients are able to stop using drugs for extended periods of time. By studying this specific group of patients, researchers want to understand the difference between those who may or may not respond to treatment. They want to study the brain while people do thinking and feeling tasks and when they relax. They will study brain chemicals, a stress hormone, and certain genes. The results may help them understand the brain basis for addiction and recovery. Objectives: To use brain imaging to find differences between people with and without drug addiction. To see if these differences help predict addiction. Eligibility: Healthy, right-handed adults ages 21-65, enrolled in a physician health program or those with no history of addiction and with at least 16 years of education Design: Participants enrolled in a PHP will be screened under this study and participants with no history of addiction will be screened under another study. At the study visit, participants will: Have a routine check-up, including tests for pregnancy, drugs, and alcohol. Give 11 blood samples. Rate their cravings. Test their frustration with stressful situations by responding to questions on a screen. Practice the magnetic resonance imaging (MRI) tasks: Shock task. Two electrodes placed on a foot will deliver brief, low-strength electrical shocks that get gradually stronger, but not painful. Participants will see drug or neutral images. They will rate their discomfort. Thinking tasks. Participants will answer questions about pictures, numbers, and money. They will press buttons in response to things they see. Do the MRI tasks in 2 sessions (morning and afternoon) in the scanner. Participants will lie in an MRI machine which will take pictures of the bra
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2019-07-10 |
| Est. Completion | 2024-04-29 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03427424
The ClinicalTrials.gov registry entry for NCT03427424 describes a study currently listed as terminated, categorized as an unspecified phase. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute on Drug Abuse (NIDA), which has 335 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT03427424 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03427424 about?
NCT03427424 is a clinical study titled "Imaging Biomarker for Addiction Treatment Outcome". Background: Many people suffer from drug addiction. But currently, treatments are not very effective. One group of patients in this study are enrolled in addiction treatment through physician health programs (PHPs). About 70% of these patients are able to stop using drugs for extended periods of ti...
What is the current status of trial NCT03427424?
This trial is currently terminated. The enrollment target is 52 participants. The study started on 2019-07-10. Estimated completion is 2024-04-29.
Who is sponsoring clinical trial NCT03427424?
This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.
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