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NCT03426605 · ClinicalTrials.gov registry record · Phase 1
A Study of LAM-003 in Patients With Acute Myeloid Leukemia
A Phase 1 study, sponsored by OrphAI Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 17
- Enrollment target
NCT03426605: Completed Phase 1 study, sponsored by OrphAI Therapeutics.
NCT03426605 is a Phase 1 study that has completed, run by OrphAI Therapeutics. The registered enrollment target is 17 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03426605, a Phase 1 study, has completed, sponsored by OrphAI Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 17 participants
- Enrollment target
Study Summary
A Phase 1 Dose-Escalation Study of LAM-003 in Patients with Acute Myeloid Leukemia
Primary Outcome
A primary objective was to determine the LAM-003 MTD and/or recommended dosing regimen (RDR) based on the pattern of dose-limiting toxicities (DLTs) in Cycle 1 of therapy. MTD as determined by DLTs.
Interventions
- DRUG Open Label LAM-003
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2018-01-16 |
| Est. Completion | 2020-10-05 |
| Phase | Phase 1 |
What the finished NCT03426605 record still lists
NCT03426605 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 1 intervention - of which Open Label LAM-003 is the first listed.
NCT03426605 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03426605 about?
NCT03426605 is a clinical study titled "A Study of LAM-003 in Patients With Acute Myeloid Leukemia". A Phase 1 Dose-Escalation Study of LAM-003 in Patients with Acute Myeloid Leukemia
What is the current status of trial NCT03426605?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2018-01-16. Estimated completion is 2020-10-05.
What interventions are being tested in trial NCT03426605?
The interventions under investigation include: Open Label LAM-003 (DRUG).
Who is sponsoring clinical trial NCT03426605?
This trial is sponsored by OrphAI Therapeutics, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03426605's enrollment target sits among peer trials
17 1785th of 2000 higher than 215 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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