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NCT03412396 · ClinicalTrials.gov registry record · Phase 2

Apalutamide in Treating Patients With Prostate Cancer Before Radical Prostatectomy

A Phase 2 study of Prostate Adenocarcinoma and Stage IIB Prostate Cancer AJCC v8, sponsored by M.D. Anderson Cancer Center.

Active
Registry status
Phase 2
Development phase
45
Enrollment target
1
Study location

NCT03412396 is a Phase 2 study of Prostate Adenocarcinoma and Stage IIB Prostate Cancer AJCC v8 that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 45 participants, below the 218-participant average among 99 other Prostate Adenocarcinoma trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03412396, a Phase 2 study of Prostate Adenocarcinoma and Stage IIB Prostate Cancer AJCC v8, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
45 participants
Enrollment target
1
Study location

Study Summary

This phase II trial studies how well apalutamide works in treating patients with prostate cancer before radical prostatectomy. Androgen can cause the growth of prostate cancer cells. Hormone therapy using apalutamide may fight prostate cancer by lowering the amount of androgen the body makes and may make it less likely for patients to receive radiation therapy after surgery.

Interventions

  • OTHER Quality-of-Life Assessment
  • DRUG Apalutamide
  • PROCEDURE Radical Prostatectomy

Study Locations (1)

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2018-03-22
Est. Completion 2026-03-30
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT03412396

The ClinicalTrials.gov registry entry for NCT03412396 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 218-participant average among 99 other Prostate Adenocarcinoma trials with a reported enrollment target (79% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Prostate Adenocarcinoma appearing as the primary indexed condition, and to 3 interventions - of which Quality-of-Life Assessment is the first listed.

NCT03412396 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT03412396 about?

NCT03412396 is a clinical study titled "Apalutamide in Treating Patients With Prostate Cancer Before Radical Prostatectomy". This phase II trial studies how well apalutamide works in treating patients with prostate cancer before radical prostatectomy. Androgen can cause the growth of prostate cancer cells. Hormone therapy using apalutamide may fight prostate cancer by lowering the amount of androgen the body makes and may...

What is the current status of trial NCT03412396?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 2018-03-22. Estimated completion is 2026-03-30.

What conditions does trial NCT03412396 study?

This clinical trial studies the following conditions: Prostate Adenocarcinoma, Stage IIB Prostate Cancer AJCC v8.

What interventions are being tested in trial NCT03412396?

The interventions under investigation include: Quality-of-Life Assessment (OTHER), Apalutamide (DRUG), Radical Prostatectomy (PROCEDURE).

Who is sponsoring clinical trial NCT03412396?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03412396 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.