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NCT03384446 · ClinicalTrials.gov registry record · NA
Dental Hygiene and Peri-Implant Tissues Homeostasis
A NA study, sponsored by University of Washington.
- Completed
- Registry status
- NA
- Development phase
- 34
- Enrollment target
NCT03384446 is a NA study that has completed, run by University of Washington. The registered enrollment target is 34 participants.
The verdict
NCT03384446, a NA study, has completed, sponsored by University of Washington.
- COMPLETED
- Registry status
- NA
- Development phase
- 34 participants
- Enrollment target
Study Summary
Dental implants have revolutionized the field of dentistry, providing improvements in function and esthetics. They are not, however, without risks. Bone loss around implants (i.e. periimplantitis) is an emerging public health concern. Untreated, peri-implantitis leads to implant loss and jawbone defects. Nonetheless, existing therapies have failed to show long-term efficacy. The pathogenesis of peri-implantitis is believed to be of bacterial etiology similar to periodontal disease. Therefore, existing treatments duplicate strategies for the treatment of natural teeth. However, the titanium (Ti) surface of implants is quite dissimilar to teeth. Recent work from our lab has demonstrated that peri-implantitis is associated with increased release of Ti particles around implants. These findings suggest that treatments targeting periimplantitis must be designed around Ti material properties. A gap in knowledge exists regarding the potential triggers of increased Ti dissolution from the implant surface and the mechanisms by which Ti dissolution products amplify peri-implant inflammation. The aim of this study is to determine if the use of tooth-driven treatment approaches increase Ti in the submucosal plaque.
Interventions
- OTHER Tooth-borne treatment
- OTHER Implant-specific treatment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2017-11-22 |
| Est. Completion | 2023-06-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03384446
The ClinicalTrials.gov registry entry for NCT03384446 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Washington, which has 1,048 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Tooth-borne treatment is the first listed.
NCT03384446 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03384446 about?
NCT03384446 is a clinical study titled "Dental Hygiene and Peri-Implant Tissues Homeostasis". Dental implants have revolutionized the field of dentistry, providing improvements in function and esthetics. They are not, however, without risks. Bone loss around implants (i.e. periimplantitis) is an emerging public health concern. Untreated, peri-implantitis leads to implant loss and jawbone def...
What is the current status of trial NCT03384446?
This trial is currently completed. It is a NA study. The enrollment target is 34 participants. The study started on 2017-11-22. Estimated completion is 2023-06-10.
What interventions are being tested in trial NCT03384446?
The interventions under investigation include: Tooth-borne treatment (OTHER), Implant-specific treatment (OTHER).
Who is sponsoring clinical trial NCT03384446?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
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