Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03379974 · ClinicalTrials.gov registry record · Phase 4
Exercise Versus DDAVP in Patients With Mild Hemophilia A
A Phase 4 study, sponsored by Nationwide Children's Hospital.
- Completed
- Registry status
- Phase 4
- Development phase
- 32
- Enrollment target
NCT03379974 is a Phase 4 study that has completed, run by Nationwide Children's Hospital. The registered enrollment target is 32 participants.
The verdict
NCT03379974, a Phase 4 study, has completed, sponsored by Nationwide Children's Hospital.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 32 participants
- Enrollment target
Study Summary
Individuals with mild hemophilia A (MHA) bleed infrequently but can in the setting of trauma which often is when participating in sports/exercise. Although both exercise and DDAVP (desmopressin) can raise Factor 8/Von Willebrand Factor (FVIII/VWF levels), it is not clear whether the pathophysiological mechanism is the same. Consequently it is not known if DDAVP and exercise would have additive effects in raising FVIII:C and VWF levels or if one would one negate the effect of the other. The aim of this 2 center (Sickkids and Nationwide Children's), prospective, cross-over design study is to compare the impact of exercise vs. DDAVP on hemostasis in patients with MHA and also to investigate the impact of sequentially administering these interventions on their hemostatic indices.
Interventions
- BEHAVIORAL Exercise Intervention
- DRUG DDAVP Inhalant Product
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2018-07-31 |
| Est. Completion | 2019-12-05 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03379974
The ClinicalTrials.gov registry entry for NCT03379974 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Nationwide Children's Hospital, which has 188 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Exercise Intervention is the first listed.
NCT03379974 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03379974 about?
NCT03379974 is a clinical study titled "Exercise Versus DDAVP in Patients With Mild Hemophilia A". Individuals with mild hemophilia A (MHA) bleed infrequently but can in the setting of trauma which often is when participating in sports/exercise. Although both exercise and DDAVP (desmopressin) can raise Factor 8/Von Willebrand Factor (FVIII/VWF levels), it is not clear whether the pathophysiologic...
What is the current status of trial NCT03379974?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 32 participants. The study started on 2018-07-31. Estimated completion is 2019-12-05.
What interventions are being tested in trial NCT03379974?
The interventions under investigation include: Exercise Intervention (BEHAVIORAL), DDAVP Inhalant Product (DRUG).
Who is sponsoring clinical trial NCT03379974?
This trial is sponsored by Nationwide Children's Hospital, which has 188 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.