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NCT03377049 · ClinicalTrials.gov registry record · Phase 4

Acetazolamide Challenge With Perfusion in the Prediction of Cerebral Vasospasm

A Phase 4 study, sponsored by University of Wisconsin, Madison.

Completed
Registry status
Phase 4
Development phase
11
Enrollment target

NCT03377049: Completed Phase 4 study, sponsored by University of Wisconsin, Madison.

NCT03377049 is a Phase 4 study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 11 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03377049, a Phase 4 study, has completed, sponsored by University of Wisconsin, Madison.

COMPLETED
Registry status
Phase 4
Development phase
11 participants
Enrollment target

Study Summary

The investigators propose a technique using cone beam CT perfusion (CBCTP) imaging with an acetazolamide challenge as a potential diagnostic tool to detect a defect in cerebral autoregulation at a time when it has not yet caused clinically apparent signs or symptoms. 30 participants will be enrolled at the University of Wisconsin - Madison and can expect to be on study for about 2 weeks.

Primary Outcome

Clinical neurological deterioration not attributable to other causes, mores specifically not due to re-bleeding, hydrocephalus, or metabolic changes.

Interventions

  • DRUG Acetazolamide

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2019-07-28
Est. Completion 2022-07-15
Phase Phase 4
University of Wisconsin, Madison

1,039 total trials

What the finished NCT03377049 record still lists

NCT03377049 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Acetazolamide is the first listed.

NCT03377049 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03377049 about?

NCT03377049 is a clinical study titled "Acetazolamide Challenge With Perfusion in the Prediction of Cerebral Vasospasm". The investigators propose a technique using cone beam CT perfusion (CBCTP) imaging with an acetazolamide challenge as a potential diagnostic tool to detect a defect in cerebral autoregulation at a time when it has not yet caused clinically apparent signs or symptoms. 30 participants will be enrolled...

What is the current status of trial NCT03377049?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 11 participants. The study started on 2019-07-28. Estimated completion is 2022-07-15.

What interventions are being tested in trial NCT03377049?

The interventions under investigation include: Acetazolamide (DRUG).

Who is sponsoring clinical trial NCT03377049?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03377049's enrollment target sits among peer trials

11 1931st of 2000 higher than 61 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03377049, the US trial registry maintained by the National Library of Medicine. NCT03377049 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.