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NCT03367871 · ClinicalTrials.gov registry record · Phase 2

Combination Pembrolizumab, Chemotherapy and Bevacizumab in Patients With Cervical Cancer

A Phase 2 study, sponsored by University of Miami.

Terminated
Registry status
Phase 2
Development phase
17
Enrollment target

NCT03367871: Clinical Trial Phase 2 study, sponsored by University of Miami.

NCT03367871 is a Phase 2 study that was terminated before completion, run by University of Miami. The registered enrollment target is 17 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03367871, a Phase 2 study, was terminated before completion, sponsored by University of Miami.

TERMINATED
Registry status
Phase 2
Development phase
17 participants
Enrollment target

Study Summary

The investigators propose to evaluate the efficacy of the combination of standard chemotherapy with bevacizumab with Pembrolizumab in women with recurrent, persistent, or metastatic cervical cancer.

Primary Outcome

Objective response defined as the percentage of patients showing complete or partial response to study therapy. Response to therapy will be evaluated using the Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1).

Interventions

  • DRUG Pembrolizumab
  • DRUG Bevacizumab
  • DRUG Carboplatin
  • DRUG Cisplatin
  • DRUG Paclitaxel

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2018-09-06
Est. Completion 2023-01-30
Phase Phase 2
University of Miami

721 total trials

Why NCT03367871 stopped before completion

NCT03367871 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (87% lower).

The record links to 0 conditions, and to 5 interventions - of which Pembrolizumab is the first listed.

NCT03367871 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03367871 about?

NCT03367871 is a clinical study titled "Combination Pembrolizumab, Chemotherapy and Bevacizumab in Patients With Cervical Cancer". The investigators propose to evaluate the efficacy of the combination of standard chemotherapy with bevacizumab with Pembrolizumab in women with recurrent, persistent, or metastatic cervical cancer.

What is the current status of trial NCT03367871?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 17 participants. The study started on 2018-09-06. Estimated completion is 2023-01-30.

What interventions are being tested in trial NCT03367871?

The interventions under investigation include: Pembrolizumab (DRUG), Bevacizumab (DRUG), Carboplatin (DRUG), Cisplatin (DRUG), Paclitaxel (DRUG).

Who is sponsoring clinical trial NCT03367871?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03367871's enrollment target sits among peer trials

17 1903rd of 2000 higher than 93 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03367871, the US trial registry maintained by the National Library of Medicine. NCT03367871 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.