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NCT03360903 · ClinicalTrials.gov registry record · Phase 4
A Study to Determine if Caffeine Accelerates Emergence From Propofol Anesthesia
A Phase 4 study, sponsored by University of Chicago.
- Completed
- Registry status
- Phase 4
- Development phase
- 8
- Enrollment target
NCT03360903 is a Phase 4 study that has completed, run by University of Chicago. The registered enrollment target is 8 participants.
The verdict
NCT03360903, a Phase 4 study, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 8 participants
- Enrollment target
Study Summary
At present clinicians have no way to reverse anesthesia. Patients wake when their bodies clear the anesthetic. Most people wake quickly, but some do not. All patients have memory and other cognitive problems after waking from anesthesia. In studies on animals, the investigators observed that caffeine caused rats to wake much more rapidly from propofol anesthesia. This was true for all the animals tested. The investigators would like to see if this holds true in humans. Will caffeine accelerate waking from anesthesia? Will it reverse the cognitive deficits associated with anesthesia, after waking? The propose investigators carrying out a modest trial with 8 test subjects. Each volunteer will be anesthetized twice. Each volunteer will be anesthetized one time and receive an infusion of saline (placebo control), without the aid of any other drugs and the other time the volunteer will receive an infusion of a relatively low dose of caffeine. The order of saline versus caffeine will be randomized and the study will be done in a double blind manner. We will determine whether emergence from propofol anesthesia will be significantly accelerated by the caffeine infusion. And whether any adverse events are observed.
Interventions
- DRUG Placebo
- DRUG Caffeine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2018-01-02 |
| Est. Completion | 2019-06-01 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03360903
The ClinicalTrials.gov registry entry for NCT03360903 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Chicago, which has 796 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT03360903 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03360903 about?
NCT03360903 is a clinical study titled "A Study to Determine if Caffeine Accelerates Emergence From Propofol Anesthesia". At present clinicians have no way to reverse anesthesia. Patients wake when their bodies clear the anesthetic. Most people wake quickly, but some do not. All patients have memory and other cognitive problems after waking from anesthesia. In studies on animals, the investigators observed that caffein...
What is the current status of trial NCT03360903?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 8 participants. The study started on 2018-01-02. Estimated completion is 2019-06-01.
What interventions are being tested in trial NCT03360903?
The interventions under investigation include: Placebo (DRUG), Caffeine (DRUG).
Who is sponsoring clinical trial NCT03360903?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
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