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NCT03344900 · ClinicalTrials.gov registry record
Re-Aiming at Hydroxyurea Adherence for Sickle Cell With mHealth
A clinical trial, sponsored by St. Jude Children's Research Hospital.
- Completed
- Registry status
- 100
- Enrollment target
NCT03344900 is a clinical trial that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 100 participants.
The verdict
NCT03344900 has completed, sponsored by St. Jude Children's Research Hospital.
- COMPLETED
- Registry status
- 100 participants
- Enrollment target
Study Summary
National Institutes of Health (NIH)/National Heart, Lung, and Blood Institute (NHLBI) guidelines recommend that hydroxyurea be offered to symptomatic adults and all children with sickle cell disease (SCD) (HbSS and HbSβ0-thal genotypes) age ≥9 months. Research has shown that hydroxyurea reduces hospitalizations and mortality, supporting its effectiveness outside of clinical trials. Hydroxyurea is given as a once-daily oral dose that costs \<$1 per day. Despite overwhelming evidence for positive effects, hydroxyurea is vastly underutilized. Given the relative ease of its administration, low cost, and safety profile, barriers to hydroxyurea utilization are primarily constrained to the health system and patient determinants. System-level barriers include insufficient access to SCD-specific care, limited access to medication (due to lack of health coverage), and providers' reluctance in prescribing it; while patient-level barriers include low acceptance (due to insufficient knowledge or misconceptions regarding risks and benefits), and forgetfulness leading to poor adherence. Mobile health (mHealth) refers to the practice of medicine and public health supported by mobile devices. Short message service (SMS) text messaging (through cell phones) is a widespread means of communication, particularly among adolescents and young adults and is an emerging intervention modality to improve medication adherence. Its low cost, simplicity, and prevalence allow for relatively easy adoption and dissemination in medical practices. This protocol seeks to examine barriers to hydroxyurea adherence among SCD patients between 15 and 45 years of age who are living in the Memphis region by conducting a needs assessment. In addition to examining these barriers, the needs assessment will provide data that will inform the development of an mHealth application (e.g. mobile phone application) for assisting patients in increasing their medication adherence. The developed mHealth intervention wil
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2017-12-05 |
| Est. Completion | 2018-06-28 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03344900
The ClinicalTrials.gov registry entry for NCT03344900 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is St. Jude Children's Research Hospital, which has 410 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT03344900 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03344900 about?
NCT03344900 is a clinical study titled "Re-Aiming at Hydroxyurea Adherence for Sickle Cell With mHealth". National Institutes of Health (NIH)/National Heart, Lung, and Blood Institute (NHLBI) guidelines recommend that hydroxyurea be offered to symptomatic adults and all children with sickle cell disease (SCD) (HbSS and HbSβ0-thal genotypes) age ≥9 months. Research has shown that hydroxyurea reduces hosp...
What is the current status of trial NCT03344900?
This trial is currently completed. The enrollment target is 100 participants. The study started on 2017-12-05. Estimated completion is 2018-06-28.
Who is sponsoring clinical trial NCT03344900?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
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