Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03335917 · ClinicalTrials.gov registry record · NA

Oxygen Transport in Normobaric vs. Hypobaric Hypoxia

A NA study, sponsored by University of Nebraska.

Completed
Registry status
NA
Development phase
12
Enrollment target

NCT03335917: Completed NA study, sponsored by University of Nebraska.

NCT03335917 is a NA study that has completed, run by University of Nebraska. The registered enrollment target is 12 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03335917, a NA study, has completed, sponsored by University of Nebraska.

COMPLETED
Registry status
NA
Development phase
12 participants
Enrollment target

Study Summary

1\) Oxygen Transport in Normobaric versus Hypobaric Hypoxia. 2) The purpose of this study is to examine acute responses in arterial and muscle tissue oxygenation during incremental exercise in normobaric versus hypobaric hypoxia. 3) The participants in this study will consist of 12 recreationally active males and females between the ages of 19 and 45.Recreationally active is defined as participating in moderate to vigorous physical activity for 30 minutes at least 3 days per week.4) Subjects will complete an incremental cycle test to volitional fatigue in three conditions in a randomized counter-balanced order, normobaric normoxia (20.9% O2, 730 mmHg), normobaric hypoxia (14.3% O2, 730 mmHg) and hypobaric hypoxia (20.9% O2, 530mmHg). Two of the three trials will be conducted in an environmental chamber to simulate normobaric normoxia at 350 m (elevation of Omaha, NE) and normobaric hypoxia at 3094 m (elevation of Leadville, CO). The hypobaric hypoxia trial will be conducted in Leadville, Colorado at 3094 m. Trials will be separated by at least two days. Rating of perceived exertion, heart rate, blood oxygenation, respiration rate, muscle tissue oxygenation, and whole body gases will be analyzed during the trials. 5) There is no follow-up as a part of this study.

Primary Outcome

% O2 sat in muscle using NIRS

Interventions

  • OTHER Exercise
  • OTHER Hypoxia

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2017-08-15
Est. Completion 2018-06-01
Phase NA
University of Nebraska

407 total trials

What the finished NCT03335917 record still lists

NCT03335917 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Exercise is the first listed.

NCT03335917 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03335917 about?

NCT03335917 is a clinical study titled "Oxygen Transport in Normobaric vs. Hypobaric Hypoxia". 1\) Oxygen Transport in Normobaric versus Hypobaric Hypoxia. 2) The purpose of this study is to examine acute responses in arterial and muscle tissue oxygenation during incremental exercise in normobaric versus hypobaric hypoxia. 3) The participants in this study will consist of 12 recreationally ac...

What is the current status of trial NCT03335917?

This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2017-08-15. Estimated completion is 2018-06-01.

What interventions are being tested in trial NCT03335917?

The interventions under investigation include: Exercise (OTHER), Hypoxia (OTHER).

Who is sponsoring clinical trial NCT03335917?

This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03335917's enrollment target sits among peer trials

12 1913th of 2000 higher than 74 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02602769 · 12 participants

    Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

  • NCT02605421 · 12 participants · Phase 2

    Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

  • NCT02619448 · 12 participants · Early Phase 1

    Concurrent Chemotherapy Plus HFR Radiation Therapy in Inoperable NSCLC

  • NCT03311503 · 12 participants · Phase 1

    Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03335917, the US trial registry maintained by the National Library of Medicine. NCT03335917 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.