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NCT03326999 · ClinicalTrials.gov registry record · Phase 4

Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?

A Phase 4 study, sponsored by Icahn School of Medicine at Mount Sinai.

Completed
Registry status
Phase 4
Development phase
60
Enrollment target

NCT03326999: Completed Phase 4 study, sponsored by Icahn School of Medicine at Mount Sinai.

NCT03326999 is a Phase 4 study that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 60 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03326999, a Phase 4 study, has completed, sponsored by Icahn School of Medicine at Mount Sinai.

COMPLETED
Registry status
Phase 4
Development phase
60 participants
Enrollment target

Study Summary

One common anesthetic that is performed for total knee replacement surgery is spinal anesthesia with an adductor canal regional block, which involves injecting numbing medication in the thigh region for pain control after surgery. The aim of this study is to determine whether the addition of another regional block called obturator nerve block, which involves injecting numbing medication in the upper thigh region, will improve pain control after surgery while not sacrificing mobility after surgery.

Primary Outcome

Total amount of opioids consumed

Interventions

  • DRUG Saline
  • DRUG Obturator nerve regional block
  • DRUG Adductor canal regional block

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2017-12-11
Est. Completion 2018-12-18
Phase Phase 4

What the finished NCT03326999 record still lists

NCT03326999 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower).

The record links to 0 conditions, and to 3 interventions - of which Saline is the first listed.

NCT03326999 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03326999 about?

NCT03326999 is a clinical study titled "Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?". One common anesthetic that is performed for total knee replacement surgery is spinal anesthesia with an adductor canal regional block, which involves injecting numbing medication in the thigh region for pain control after surgery. The aim of this study is to determine whether the addition of another...

What is the current status of trial NCT03326999?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2017-12-11. Estimated completion is 2018-12-18.

What interventions are being tested in trial NCT03326999?

The interventions under investigation include: Saline (DRUG), Obturator nerve regional block (DRUG), Adductor canal regional block (DRUG).

Who is sponsoring clinical trial NCT03326999?

This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03326999's enrollment target sits among peer trials

60 1125th of 2000 higher than 799 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03326999, the US trial registry maintained by the National Library of Medicine. NCT03326999 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.