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NCT03310125 · ClinicalTrials.gov registry record · Phase 3
Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)
A Phase 3 study, sponsored by Population Health Research Institute.
- Completed
- Registry status
- Phase 3
- Development phase
- 3,209
- Enrollment target
NCT03310125: Completed Phase 3 study, sponsored by Population Health Research Institute.
NCT03310125 is a Phase 3 study that has completed, run by Population Health Research Institute. The registered enrollment target is 3,209 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (316% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03310125, a Phase 3 study, has completed, sponsored by Population Health Research Institute.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 3,209 participants
- Enrollment target
Study Summary
The prevention of perioperative atrial fibrillation (AF) and myocardial injury after non-cardiac surgery (MINS) has the potential to reduce mortality, stroke, and hospital stays in patients undergoing major thoracic surgery. Data from cardiac surgery patients suggest that prevention of perioperative atrial fibrillation using an anti-inflammatory agent, such as colchicine, is feasible. The COP-AF trial will assess whether the administration of oral colchicine will reduce the incidence of perioperative atrial fibrillation and myocardial injury after non-cardiac surgery in patients undergoing major thoracic surgery.
Interventions
- DRUG Placebo
- DRUG Colchicine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,209 participants |
| Start Date | 2018-02-14 |
| Est. Completion | 2023-07-26 |
| Phase | Phase 3 |
What the finished NCT03310125 record still lists
NCT03310125 is an interventional study that assigns participants to a tested intervention. Its 3,209 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (316% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT03310125 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03310125 about?
NCT03310125 is a clinical study titled "Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)". The prevention of perioperative atrial fibrillation (AF) and myocardial injury after non-cardiac surgery (MINS) has the potential to reduce mortality, stroke, and hospital stays in patients undergoing major thoracic surgery. Data from cardiac surgery patients suggest that prevention of perioperative...
What is the current status of trial NCT03310125?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 3,209 participants. The study started on 2018-02-14. Estimated completion is 2023-07-26.
What interventions are being tested in trial NCT03310125?
The interventions under investigation include: Placebo (DRUG), Colchicine (DRUG).
Who is sponsoring clinical trial NCT03310125?
This trial is sponsored by Population Health Research Institute, which has 21 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03310125's enrollment target sits among peer trials
3,209 73rd of 2000 higher than 1,928 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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