Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03306615 · ClinicalTrials.gov registry record · Phase 2
Peripheral Modulation of Muscle Stiffness and Spasticity
A Phase 2 study of Muscle Spasticity, sponsored by Johns Hopkins University.
- Active
- Registry status
- Phase 2
- Development phase
- 56
- Enrollment target
- 1
- Study location
NCT03306615 is a Phase 2 study of Muscle Spasticity that is active but no longer recruiting, run by Johns Hopkins University. The registered enrollment target is 56 participants, below the 75-participant average among 8 other Muscle Spasticity trials with a reported enrollment target (25% lower). The trial reports 1 study location across 1 state.
The verdict
NCT03306615, a Phase 2 study of Muscle Spasticity, is active but no longer recruiting, sponsored by Johns Hopkins University.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 56 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a single-center, double-blind, randomized, placebo-controlled, sequential Phase II trial of human recombinant hyaluronidase injections in individuals with post-stroke upper limb muscle stiffness. The investigators will recruit 56 subjects, who will be randomized to receive either the intervention or normal saline injections (first injection), and then the intervention the participants did not receive first (second injection). All individuals will receive the treatment by the end of the study.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Hyaluronidase
Study Locations (1)
Maryland
- Johns Hopkins School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2021-10-11 |
| Est. Completion | 2026-06-30 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03306615
The ClinicalTrials.gov registry entry for NCT03306615 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 75-participant average among 8 other Muscle Spasticity trials with a reported enrollment target (25% lower). The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Muscle Spasticity appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT03306615 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT03306615 about?
NCT03306615 is a clinical study titled "Peripheral Modulation of Muscle Stiffness and Spasticity". This is a single-center, double-blind, randomized, placebo-controlled, sequential Phase II trial of human recombinant hyaluronidase injections in individuals with post-stroke upper limb muscle stiffness. The investigators will recruit 56 subjects, who will be randomized to receive either the interve...
What is the current status of trial NCT03306615?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 56 participants. The study started on 2021-10-11. Estimated completion is 2026-06-30.
What conditions does trial NCT03306615 study?
This clinical trial studies the following conditions: Muscle Spasticity.
What interventions are being tested in trial NCT03306615?
The interventions under investigation include: Placebo (DRUG), Hyaluronidase (DRUG).
Who is sponsoring clinical trial NCT03306615?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03306615 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Muscle Spasticity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Botulinum Toxin (BOTOX) for Cerebral Palsy
COMPLETED · Phase 2
-
Exoskeleton and Spinal Cord Stimulation for SCI
RECRUITING · NA
-
Dry Needling for Spasticity in Stroke
ACTIVE NOT RECRUITING · NA
-
Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity
COMPLETED
-
Using Telemedicine to Improve Spasticity Diagnosis Rates
COMPLETED
-
Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury
COMPLETED · Phase 3
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.