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NCT03304652 · ClinicalTrials.gov registry record
Cerebral MRI During Sleep
A clinical trial, sponsored by University of California, San Diego.
- Completed
- Registry status
- 11
- Enrollment target
NCT03304652: Completed study, sponsored by University of California, San Diego.
NCT03304652 is a clinical trial that has completed, run by University of California, San Diego. The registered enrollment target is 11 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03304652 has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- 11 participants
- Enrollment target
Study Summary
Recent studies in animal models have suggested a critical role for cerebrospinal fluid and Interstitial fluid flux through cerebral parenchyma for removal of byproducts of cellular metabolism and hence in maintaining the health of the brain. This effect is modulated during sleep, suggesting a potentially important mechanism for sleep to maintain both acute homeostasis and long-term cerebral health. The central goal of these studies is to develop a sensitive MRI biomarker of cerebral conformational changes during sleep. This exploratory work aims to establish the sensitivity and reproducibility of MRI as a non-invasive neuroimaging assessment of cerebral changes during natural sleep and sedation.
Primary Outcome
Change in MRI Signal from Awake Baseline
Interventions
- DRUG Zaleplon
- OTHER Natural Sleep
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2017-10-01 |
| Est. Completion | 2018-10-31 |
What the finished NCT03304652 record still lists
NCT03304652 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 11 participants, a relatively small participant target.
The record links to 0 conditions, and to 2 interventions - of which Zaleplon is the first listed.
NCT03304652 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03304652 about?
NCT03304652 is a clinical study titled "Cerebral MRI During Sleep". Recent studies in animal models have suggested a critical role for cerebrospinal fluid and Interstitial fluid flux through cerebral parenchyma for removal of byproducts of cellular metabolism and hence in maintaining the health of the brain. This effect is modulated during sleep, suggesting a potent...
What is the current status of trial NCT03304652?
This trial is currently completed. The enrollment target is 11 participants. The study started on 2017-10-01. Estimated completion is 2018-10-31.
What interventions are being tested in trial NCT03304652?
The interventions under investigation include: Zaleplon (DRUG), Natural Sleep (OTHER).
Who is sponsoring clinical trial NCT03304652?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
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