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NCT03300817 · ClinicalTrials.gov registry record · Phase 1

MUC1 Vaccine in Preventing Lung Cancer in Current and Former Smokers at High Risk for Lung Cancer

A Phase 1 study of Lung Carcinoma, sponsored by National Cancer Institute (NCI).

Active
Registry status
Phase 1
Development phase
50
Enrollment target
2
Study locations

NCT03300817: Active Phase 1 study of Lung Carcinoma, sponsored by National Cancer Institute (NCI).

NCT03300817 is a Phase 1 study of Lung Carcinoma that is active but no longer recruiting, run by National Cancer Institute (NCI). The registered enrollment target is 50 participants, below the 5,042-participant average among 38 other Lung Carcinoma trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03300817, a Phase 1 study of Lung Carcinoma, is active but no longer recruiting, sponsored by National Cancer Institute (NCI).

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
50 participants
Enrollment target
2
Study locations

Study Summary

This pilot phase I trial studies the side effects and how well MUC1 peptide-Poly-ICLC vaccine works in preventing lung cancer in current and former smokers at high risk for lung cancer. Vaccines made from peptides may help the body build an effective immune response to kill cells. MUC1 peptide-Poly-ICLC vaccine may stimulate the body's immune system and slow or stop the changes from normal to pre-cancer to cancer.

Conditions Studied

Interventions

  • OTHER Laboratory Biomarker Analysis
  • BIOLOGICAL MUC1 Peptide-Poly-ICLC Vaccine

Study Locations (2)

Minnesota

  • Mayo Clinic in Rochester - Rochester

Pennsylvania

  • University of Pittsburgh Cancer Institute (UPCI) - Pittsburgh

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2017-12-27
Est. Completion 2025-12-01
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT03300817

The ClinicalTrials.gov registry entry for NCT03300817 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,042-participant average among 38 other Lung Carcinoma trials with a reported enrollment target (99% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Lung Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT03300817 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Minnesota, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT03300817 about?

NCT03300817 is a clinical study titled "MUC1 Vaccine in Preventing Lung Cancer in Current and Former Smokers at High Risk for Lung Cancer". This pilot phase I trial studies the side effects and how well MUC1 peptide-Poly-ICLC vaccine works in preventing lung cancer in current and former smokers at high risk for lung cancer. Vaccines made from peptides may help the body build an effective immune response to kill cells. MUC1 peptide-Poly-...

What is the current status of trial NCT03300817?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2017-12-27. Estimated completion is 2025-12-01.

What conditions does trial NCT03300817 study?

This clinical trial studies the following conditions: Lung Carcinoma.

What interventions are being tested in trial NCT03300817?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), MUC1 Peptide-Poly-ICLC Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT03300817?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03300817 being conducted?

This trial has 2 study locations across Minnesota, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.