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NCT03300232 · ClinicalTrials.gov registry record · NA
Adapting an Effective CBT for Comorbidity to a Computer-Delivered Format
A NA study, sponsored by University of Minnesota.
- Completed
- Registry status
- NA
- Development phase
- 59
- Enrollment target
NCT03300232 is a NA study that has completed, run by University of Minnesota. The registered enrollment target is 59 participants.
The verdict
NCT03300232, a NA study, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- NA
- Development phase
- 59 participants
- Enrollment target
Study Summary
Up to one-half of those in treatment for alcohol use disorder (AUD) has a co-occurring anxiety disorder ("comorbidity"), a condition that marks a high degree of treatment resistance, severity and relapse risk in AUD treatment patients. The investigators conceptualize comorbidity as a feed-forward system ("vicious cycle", \[VC\]) of interacting negative affect/stress, drinking motives/behavior, coping skills deficits, environmental circumstances, and neurobiological adaptations. Based on this model, the investigators developed and validated the VC cognitive-behavioral therapy (VC-CBT) to disrupt this system at several key linkage points. In a recently completed randomized controlled trial (RCT), the investigators found that adding the VC-CBT to standard AUD inpatient treatment resulted in better alcohol outcomes 4 months following treatment than did adding an anxiety treatment or standard AUD treatment alone. With a number needed to treat (NNT) index of 8 (relative to standard AUD treatment alone), the VC-CBT could, if broadly disseminated, have a large positive impact on AUD treatment. Unfortunately, several significant barriers related to the resource- and expertise-intensive delivery of the VC-CBT limit its dissemination potential and, hence, the impact of this otherwise effective treatment. Therefore, to maximize the public health and scientific potential of the investigators work, the investigators propose to adapt the therapist-delivered VC-CBT to a computer-delivered format to facilitate reliable and economical dissemination of the VC-CBT while maintaining its established efficacy.
Interventions
- BEHAVIORAL Computer-based VC-CBT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 59 participants |
| Start Date | 2018-04-16 |
| Est. Completion | 2021-07-26 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03300232
The ClinicalTrials.gov registry entry for NCT03300232 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 59 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Computer-based VC-CBT is the first listed.
NCT03300232 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03300232 about?
NCT03300232 is a clinical study titled "Adapting an Effective CBT for Comorbidity to a Computer-Delivered Format". Up to one-half of those in treatment for alcohol use disorder (AUD) has a co-occurring anxiety disorder ("comorbidity"), a condition that marks a high degree of treatment resistance, severity and relapse risk in AUD treatment patients. The investigators conceptualize comorbidity as a feed-forward sy...
What is the current status of trial NCT03300232?
This trial is currently completed. It is a NA study. The enrollment target is 59 participants. The study started on 2018-04-16. Estimated completion is 2021-07-26.
What interventions are being tested in trial NCT03300232?
The interventions under investigation include: Computer-based VC-CBT (BEHAVIORAL).
Who is sponsoring clinical trial NCT03300232?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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