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NCT03277482 · ClinicalTrials.gov registry record · Phase 1
Durvalumab, Tremelimumab + Radiotherapy in Gynecologic Cancer
A Phase 1 study, sponsored by Dana-Farber Cancer Institute.
- Terminated
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT03277482: Clinical Trial Phase 1 study, sponsored by Dana-Farber Cancer Institute.
NCT03277482 is a Phase 1 study that was terminated before completion, run by Dana-Farber Cancer Institute. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03277482, a Phase 1 study, was terminated before completion, sponsored by Dana-Farber Cancer Institute.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
This research study is evaluating the safety and effectiveness of 2 immunotherapy drugs in combination with radiation therapy as a possible treatment for recurrent or metastatic gynecologic cancer. The names of the immunotherapy drugs involved in this study are: * Durvalumab * Tremelimumab
Primary Outcome
Incidence of dose-limiting toxicities for each dose level or regimen
Interventions
- RADIATION Radiation Therapy
- DRUG Durvalumab
- DRUG Tremelimumab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2018-06-01 |
| Est. Completion | 2022-07-15 |
| Phase | Phase 1 |
Why NCT03277482 stopped before completion
NCT03277482 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 3 interventions - of which Radiation Therapy is the first listed.
NCT03277482 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03277482 about?
NCT03277482 is a clinical study titled "Durvalumab, Tremelimumab + Radiotherapy in Gynecologic Cancer". This research study is evaluating the safety and effectiveness of 2 immunotherapy drugs in combination with radiation therapy as a possible treatment for recurrent or metastatic gynecologic cancer. The names of the immunotherapy drugs involved in this study are: * Durvalumab * Tremelimumab
What is the current status of trial NCT03277482?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2018-06-01. Estimated completion is 2022-07-15.
What interventions are being tested in trial NCT03277482?
The interventions under investigation include: Radiation Therapy (RADIATION), Durvalumab (DRUG), Tremelimumab (DRUG).
Who is sponsoring clinical trial NCT03277482?
This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03277482's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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