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NCT03274453 · ClinicalTrials.gov registry record · Phase 2
A Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion
A Phase 2 study, sponsored by NYU Langone Health.
- Completed
- Registry status
- Phase 2
- Development phase
- 129
- Enrollment target
NCT03274453: Completed Phase 2 study, sponsored by NYU Langone Health.
NCT03274453 is a Phase 2 study that has completed, run by NYU Langone Health. The registered enrollment target is 129 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03274453, a Phase 2 study, has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 129 participants
- Enrollment target
Study Summary
The aim of the proposed study is to examine the effectiveness of low dose postoperative ketamine infusion as an analgesic adjuvant to morphine pca in opioid tolerant and opioid naïve patients after major spine surgery. Primary endpoints of the study are to determine the effectiveness of postoperative ketamine infusion in for the reduction of postoperative pain and opioid requirements.
Primary Outcome
Hydromorphone use during the first postoperative 24 hours in mg/kg
Interventions
- DRUG Ketamine
- DRUG Saline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 129 participants |
| Start Date | 2012-11-01 |
| Est. Completion | 2017-09 |
| Phase | Phase 2 |
What the finished NCT03274453 record still lists
NCT03274453 is an interventional study that assigns participants to a tested intervention. The registered 129 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Ketamine is the first listed.
NCT03274453 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03274453 about?
NCT03274453 is a clinical study titled "A Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion". The aim of the proposed study is to examine the effectiveness of low dose postoperative ketamine infusion as an analgesic adjuvant to morphine pca in opioid tolerant and opioid naïve patients after major spine surgery. Primary endpoints of the study are to determine the effectiveness of postoperativ...
What is the current status of trial NCT03274453?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 129 participants. The study started on 2012-11-01. Estimated completion is 2017-09.
What interventions are being tested in trial NCT03274453?
The interventions under investigation include: Ketamine (DRUG), Saline (DRUG).
Who is sponsoring clinical trial NCT03274453?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03274453's enrollment target sits among peer trials
129 553rd of 2000 higher than 1,448 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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