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NCT03271489 · ClinicalTrials.gov registry record · Phase 3

Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women

A Phase 3 study, sponsored by AbbVie.

Completed
Registry status
Phase 3
Development phase
478
Enrollment target

NCT03271489 is a Phase 3 study that has completed, run by AbbVie. The registered enrollment target is 478 participants.

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The verdict

NCT03271489, a Phase 3 study, has completed, sponsored by AbbVie.

COMPLETED
Registry status
Phase 3
Development phase
478 participants
Enrollment target

Study Summary

This randomized multicenter phase 3b study seeks to evaluate the safety of elagolix in combination with estradiol/norethindrone acetate for the management of heavy menstrual bleeding associated with uterine fibroids in premenopausal women. This study was double-blind (DB) during the first 12 months and open-label (OL) for the next 36 months.

Interventions

  • DRUG Elagolix
  • DRUG Estradiol /norethindrone acetate (E2/NETA)
  • OTHER E2/NETA Placebo
  • OTHER Elagolix Placebo

Trial Details

FieldValue
Enrollment Target 478 participants
Start Date 2017-09-13
Est. Completion 2024-06-28
Phase Phase 3

Sponsor

AbbVie

526 total trials

What the Registry Record Tells You About NCT03271489

The ClinicalTrials.gov registry entry for NCT03271489 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 478 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AbbVie, which has 526 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Elagolix is the first listed.

NCT03271489 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03271489 about?

NCT03271489 is a clinical study titled "Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women". This randomized multicenter phase 3b study seeks to evaluate the safety of elagolix in combination with estradiol/norethindrone acetate for the management of heavy menstrual bleeding associated with uterine fibroids in premenopausal women. This study was double-blind (DB) during the first 12 months ...

What is the current status of trial NCT03271489?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 478 participants. The study started on 2017-09-13. Estimated completion is 2024-06-28.

What interventions are being tested in trial NCT03271489?

The interventions under investigation include: Elagolix (DRUG), Estradiol /norethindrone acetate (E2/NETA) (DRUG), E2/NETA Placebo (OTHER), Elagolix Placebo (OTHER).

Who is sponsoring clinical trial NCT03271489?

This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.