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NCT03257644 · ClinicalTrials.gov registry record · Phase 1
A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic Dermatitis
A Phase 1 study, sponsored by Incyte Corporation.
- Completed
- Registry status
- Phase 1
- Development phase
- 70
- Enrollment target
NCT03257644: Completed Phase 1 study, sponsored by Incyte Corporation.
NCT03257644 is a Phase 1 study that has completed, run by Incyte Corporation. The registered enrollment target is 70 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03257644, a Phase 1 study, has completed, sponsored by Incyte Corporation.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 70 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the safety, tolerability and the pharmacokinetics (PK) of topical ruxolitinib cream applied to pediatric subjects (age ≥ 2 to 17 years) with atopic dermatitis (AD).
Primary Outcome
A TEAE is any adverse event (AE) either reported for the first time or worsening of a pre-existing event after first application of study drug.
Interventions
- DRUG Ruxolitinib phosphate cream
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2017-09-21 |
| Est. Completion | 2020-10-07 |
| Phase | Phase 1 |
What the finished NCT03257644 record still lists
NCT03257644 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher).
The record links to 0 conditions, and to 1 intervention - of which Ruxolitinib phosphate cream is the first listed.
NCT03257644 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03257644 about?
NCT03257644 is a clinical study titled "A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic Dermatitis". The purpose of this study is to evaluate the safety, tolerability and the pharmacokinetics (PK) of topical ruxolitinib cream applied to pediatric subjects (age ≥ 2 to 17 years) with atopic dermatitis (AD).
What is the current status of trial NCT03257644?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2017-09-21. Estimated completion is 2020-10-07.
What interventions are being tested in trial NCT03257644?
The interventions under investigation include: Ruxolitinib phosphate cream (DRUG).
Who is sponsoring clinical trial NCT03257644?
This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03257644's enrollment target sits among peer trials
70 749th of 2000 higher than 1,227 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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