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NCT03255824 · ClinicalTrials.gov registry record · Phase 4
A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation
A Phase 4 study, sponsored by Montefiore Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 144
- Enrollment target
NCT03255824: Completed Phase 4 study, sponsored by Montefiore Medical Center.
NCT03255824 is a Phase 4 study that has completed, run by Montefiore Medical Center. The registered enrollment target is 144 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03255824, a Phase 4 study, has completed, sponsored by Montefiore Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 144 participants
- Enrollment target
Study Summary
Hypothesis: A combination of midazolam with dexmedetomidine for sedation during third molar surgery will provide 1) superior patient satisfaction, 2) superior operator satisfaction and 3) no significant hemodynamic or respiratory changes when compared to a sedation combination of midazolam, fentanyl and propofol for sedation during third molar surgery.
Primary Outcome
To compare the groups regarding the number of respiratory events requiring intervention, described as: Chin lift/jaw thrust, Tongue thrust, Yankauer suctioning, Positive pressure oxygen administration, Placement of an oral or nasal airway.
Interventions
- DRUG Dexmedetomidine and Midazolam
- DRUG Propofol, Midazolam, and Fentanyl
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 144 participants |
| Start Date | 2018-03-20 |
| Est. Completion | 2019-12-27 |
| Phase | Phase 4 |
What the finished NCT03255824 record still lists
NCT03255824 is an interventional study that assigns participants to a tested intervention. The registered 144 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 2 interventions - of which Dexmedetomidine and Midazolam is the first listed.
NCT03255824 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03255824 about?
NCT03255824 is a clinical study titled "A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation". Hypothesis: A combination of midazolam with dexmedetomidine for sedation during third molar surgery will provide 1) superior patient satisfaction, 2) superior operator satisfaction and 3) no significant hemodynamic or respiratory changes when compared to a sedation combination of midazolam, fentanyl...
What is the current status of trial NCT03255824?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 144 participants. The study started on 2018-03-20. Estimated completion is 2019-12-27.
What interventions are being tested in trial NCT03255824?
The interventions under investigation include: Dexmedetomidine and Midazolam (DRUG), Propofol, Midazolam, and Fentanyl (DRUG).
Who is sponsoring clinical trial NCT03255824?
This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03255824's enrollment target sits among peer trials
144 577th of 2000 higher than 1,421 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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