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NCT03255629 · ClinicalTrials.gov registry record · Phase 1
Closed-Loop Glucagon Pump for Treatment of Post-Bariatric Hypoglycemia
A Phase 1 study, sponsored by Joslin Diabetes Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
NCT03255629: Completed Phase 1 study, sponsored by Joslin Diabetes Center.
NCT03255629 is a Phase 1 study that has completed, run by Joslin Diabetes Center. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03255629, a Phase 1 study, has completed, sponsored by Joslin Diabetes Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
Study Summary
To assess the efficacy of a closed loop glucagon system to prevent and treat hypoglycemia occurring in patients with Post-Bariatric Hypoglycemia (PBH) in response to meals and exercise.
Primary Outcome
A primary endpoint for this study is the prevention of meal provoked hypoglycemia, defined as sensor glucose levels below \<65 mg/dl, comparing study drug to control.
Interventions
- DRUG glucagon
- DEVICE Closed loop glucagon pump
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2017-09-19 |
| Est. Completion | 2018-08-22 |
| Phase | Phase 1 |
What the finished NCT03255629 record still lists
NCT03255629 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which glucagon is the first listed.
NCT03255629 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03255629 about?
NCT03255629 is a clinical study titled "Closed-Loop Glucagon Pump for Treatment of Post-Bariatric Hypoglycemia". To assess the efficacy of a closed loop glucagon system to prevent and treat hypoglycemia occurring in patients with Post-Bariatric Hypoglycemia (PBH) in response to meals and exercise.
What is the current status of trial NCT03255629?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2017-09-19. Estimated completion is 2018-08-22.
What interventions are being tested in trial NCT03255629?
The interventions under investigation include: glucagon (DRUG), Closed loop glucagon pump (DEVICE).
Who is sponsoring clinical trial NCT03255629?
This trial is sponsored by Joslin Diabetes Center, which has 73 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03255629's enrollment target sits among peer trials
18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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