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NCT03245944 · ClinicalTrials.gov registry record · NA

Optimal Timing of Percutaneous Intervention in Non-maturing Dialysis Fistulas

A NA study of Immature Arteriovenous Fistula, sponsored by University of Alabama at Birmingham.

Completed
Registry status
NA
Development phase
8
Enrollment target
1
Study location

NCT03245944: Completed NA study of Immature Arteriovenous Fistula, sponsored by University of Alabama at Birmingham.

NCT03245944 is a NA study of Immature Arteriovenous Fistula that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 8 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03245944, a NA study of Immature Arteriovenous Fistula, has completed, sponsored by University of Alabama at Birmingham.

COMPLETED
Registry status
NA
Development phase
8 participants
Enrollment target
1
Study location

Study Summary

Arteriovenous fistulas (AVFs) are the preferred type of vascular access for dialysis, but many of them fail to mature. The optimal timing of intervention to salvage immature AVFs is unknown.The study proposes a randomized clinical trial comparing the clinical and economic impact of early vs late angioplasty in non-maturing AVFs. The study proposes a RCT to test the hypothesis that, as compared to early angioplasty of non-maturing AVFs, late angioplasty results in a lower proportion of AVFs being used at 6 months, but a greater long-term AVF patency , lower requirement of subsequent interventions to maintain AVF patency for dialysis, and lower overall cost of access maintenance.

Primary Outcome

Ultrasound of the fistula: Mature fistula Criteria: 1. Blood flow of at least 500 ml/min and 2. Minimum diameter of 4 mm

Interventions

  • PROCEDURE early Angioplasty
  • PROCEDURE late Angioplasty

Study Locations (1)

Alabama

  • UAB - Birmingham

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2018-03-01
Est. Completion 2020-03-01
Phase NA
University of Alabama at Birmingham

1,160 total trials

What the finished NCT03245944 record still lists

NCT03245944 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Immature Arteriovenous Fistula appearing as the primary indexed condition, and to 2 interventions - of which early Angioplasty is the first listed.

NCT03245944 reports a single indexed study location in Alabama.

Frequently Asked Questions

What is clinical trial NCT03245944 about?

NCT03245944 is a clinical study titled "Optimal Timing of Percutaneous Intervention in Non-maturing Dialysis Fistulas". Arteriovenous fistulas (AVFs) are the preferred type of vascular access for dialysis, but many of them fail to mature. The optimal timing of intervention to salvage immature AVFs is unknown.The study proposes a randomized clinical trial comparing the clinical and economic impact of early vs late ang...

What is the current status of trial NCT03245944?

This trial is currently completed. It is a NA study. The enrollment target is 8 participants. The study started on 2018-03-01. Estimated completion is 2020-03-01.

What conditions does trial NCT03245944 study?

This clinical trial studies the following conditions: Immature Arteriovenous Fistula.

What interventions are being tested in trial NCT03245944?

The interventions under investigation include: early Angioplasty (PROCEDURE), late Angioplasty (PROCEDURE).

Who is sponsoring clinical trial NCT03245944?

This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03245944 being conducted?

This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT03245944's enrollment target sits among peer trials

8 1976th of 2000 higher than 19 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03245944, the US trial registry maintained by the National Library of Medicine. NCT03245944 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.