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NCT03236857 · ClinicalTrials.gov registry record · Phase 1

A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies

A Phase 1 study, sponsored by AbbVie.

Completed
Registry status
Phase 1
Development phase
143
Enrollment target

NCT03236857 is a Phase 1 study that has completed, run by AbbVie. The registered enrollment target is 143 participants.

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The verdict

NCT03236857, a Phase 1 study, has completed, sponsored by AbbVie.

COMPLETED
Registry status
Phase 1
Development phase
143 participants
Enrollment target

Study Summary

An open-label, global, multi-center study to evaluate the safety and pharmacokinetics of venetoclax monotherapy, to determine the dose limiting toxicity (DLT) and the recommended Phase 2 dose (RPTD), and to assess the preliminary efficacy of venetoclax in pediatric and young adult participants with relapsed or refractory malignancies.

Interventions

  • DRUG venetoclax
  • DRUG chemotherapy

Trial Details

FieldValue
Enrollment Target 143 participants
Start Date 2017-11-08
Est. Completion 2023-04-19
Phase Phase 1

Sponsor

AbbVie

526 total trials

What the Registry Record Tells You About NCT03236857

The ClinicalTrials.gov registry entry for NCT03236857 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 143 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AbbVie, which has 526 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which venetoclax is the first listed.

NCT03236857 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03236857 about?

NCT03236857 is a clinical study titled "A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies". An open-label, global, multi-center study to evaluate the safety and pharmacokinetics of venetoclax monotherapy, to determine the dose limiting toxicity (DLT) and the recommended Phase 2 dose (RPTD), and to assess the preliminary efficacy of venetoclax in pediatric and young adult participants with ...

What is the current status of trial NCT03236857?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 143 participants. The study started on 2017-11-08. Estimated completion is 2023-04-19.

What interventions are being tested in trial NCT03236857?

The interventions under investigation include: venetoclax (DRUG), chemotherapy (DRUG).

Who is sponsoring clinical trial NCT03236857?

This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.